Discover and read the best of Twitter Threads about #neurological

Most recents (15)

As some of you know im suffering weird #neurological symptoms atm. The last week has been pretty awful. One of the weirder symptoms is called micrographia: writing getting smaller and smaller.
↙️ My writing on Tuesday (bad not awful day)
My writing on Wednesday (awful day) ↘️ The words: corporate → research & development Location: coThe words: brief [blanked out] on extension Written in small
Micrographia in itself *can* be an early sign of conditions like #Parkinsons

In patients with Parkinsons, closing their eyes whilst writing can often help mitigate micrographia
(in my case the rapid onset followed by rapid improvement makes me think / hope its just whatever the fuck is going on with my neuro-immunology not a sign of whats to come...😬)
Read 5 tweets
Reducing #COVID19 #Airborne #Transmission Risks on #PublicTransportation Buses
» doi.org/10.1101/2021.0…
Wearing of #facemasks reduced the overall particle count released into the bus by an average of 50%, the dispersion distance by several feet and #aerosol particles by 84.36%. Image
🔝#SARSCoV2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
» doi.org/10.1016/j.jacb…
#COVID19 can kill heart muscle cells, interfere with contraction. Details of how #coronavirus infects #heart: models of tissue damage may help develop potential therapies. Image
High-content screening of coronavirus genes for innate immune suppression reveals enhanced potency of SARS-CoV-2 proteins
» doi.org/10.1101/2021.0…
196 protein products of seven coronaviruses: the genes encoded by #SARSCoV2 are generally more potent immune suppressors than others Image
Read 236 tweets
⚠️#Ocular #MRI Findings in Patients with Severe #COVID19: A Retrospective Multicenter Observational Study
» doi.org/10.1148/radiol…
All patients had nodules in the macular region, 8/9 (89%) had bilateral nodules, 2/9 (22%) had nodules outside the macular region. Screening needed. Image
⚠️🔝New-Onset #IgG #Autoantibodies in Hospitalized Patients with #COVID19
» doi.org/10.1101/2021.0…
An international team of researchers studying COVID-19 has made a startling and pivotal discovery: The virus appears to cause the body to make weapons to attack its own tissues. Image
⚠️🔝Patterns of myocardial injury in recovered troponin-positive COVID-19 patients assessed by cardiovascular magnetic resonance
» academic.oup.com/eurheartj/adva…
Damage to the heart found in more than half of #COVID19 patients discharged from hospital who show raised levels of troponin. Image
Read 235 tweets
"#ChronicPain on the #Brain - 4 #Psychological Effects of Living With #pain"
1)
Researcg covering the different ways the brain processes pain show us that the brain reacts differently to short-term pain than it does to long-lasting pain. h-wave.com/blog/chronic-p…
2)contd....
When the body experiences the latter, it can change the #centralnervoussystem (CNS),& influence sensory, emotional,& modular circuits that would otherwise inhibit pain.
3)contind.....
#chronicpain is now looked at as a #neurological #disease of it's own- comorbid with symptoms of #anxiety and #depression

#mesh injured are suffering on many levels....
Pleaee do NOT underestimate the psychological impact of living with daily chronic #pelvicpain
Read 6 tweets
Brain imaging shows we're more empathetic to others' #pain if we share skin color. Explicit bias is equal in members of majority & minority groups, but implicit bias is higher in members of the majority, an impt finding for policing & medicine. /thread onlinelibrary.wiley.com/doi/full/10.10…
The perception or imagination of someone else's #pain kicks off activity in the parts of our brains that process our own pain, #fMRI imagining reveals. This "embodied empathy" is "tuned by a variety of factors," including individuals' personalities, relationships, & experiences.
"Culturally acquired implicit attitudes & perceived similarity/familiarity" also shape our “emotional responses to others' physical #pain.”

"Considerable evidence" from #brain imaging shows we make evaluations based on "race" w/in "milliseconds even when processed subliminally."
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If you really want to make a change in the world, do something hard like #nonviolent #resistance. Read up and learn #satyagraha or change. It takes #strength & #courage; physical force is forbidden even in the so-called most favorable circumstances.

satyagrahafoundation.org/satyagraha-the…
If your cause is #righteous, Gandhi believed, the movement would speak for itself.

My personal justification for it is #psychological/#neurological (#CNS/#HPA).

If you use #violence, well the one with the biggest #ego or the biggest ego-extension (guns, tanks, war) will win.
Removing tools of violence (words, arms) from the equation, you form a mirror.

It's not easy though. You'd have to refine/drop/manage/elevate past your own #ego.

People - depending on personal history & psychology - sometimes become enraged at what they see in the #mirror.
Read 8 tweets
1/ Classic #opticneuritis is characterized by a sub-acute loss of vision in one Eye, with central #scotoma, pain on #eyemovement, positive #RAPD
- Fundus exam is usually normal
- Age range 15-45 years
2/Talking about #MOGAntibodies:
- More frequent in #pediatric population, Associated with #ADEM
- #MOG IgG serum titers depend on disease activity and is mainly from extrathecal origin, enters #CNS from systemic circulation and reaches CSF through passive diffusion or broken #BBB
Read 10 tweets
Awesome study used mice + human brain organiod model to show #COVID-19 can infect the CNS/#brain, where it specifically infected radial #glia, neural stem cells + #neurons. The #virus altered the #metabolism of the neurons it infected + cld use neuron cell machinery to replicate
2/ It’s not surprising that #COVID-19 can infect neurons given the nasal cavity is connected to the #CNS via the cribriform plate, olfactory epithelium + #nerve. This led the team to state that “the brain should be considered a high-risk organ system upon #respiratory exposure”
3/ The team also showed that, at least in some #COVID-19 patients w/ #neurological symptoms, there is a robust antibody response to the #virus in the #cerebrospinal fluid (CSF). In fact, CSF-containing antiviral #antibodies blocked COVID-19 infection in brain organoids
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My 43 #goals for the #43rdParliament #canpoli #cdnpoliKeep your promises
1.Work with Opposition not in opposition
2.Change Minister for Women and Gender Equality to Minister of Women and Gender Equity. Equality and equity are not the same thing.
3. Remove the Rural Economic Development component from the Minister for Women and Gender. It should stand alone or be added to Agriculture.
4. 42nd Parliament goal=Women & Gender should stand alone. When considering intersecting identities, the Minister has plenty on her plate
5.Increase the number of Black people in Cabinet.
6.Increase the number of Black people in Governor-in-Council appointments.
7.Name an experienced Black individual to head the new Anti-Racism Secretariat within the Department of Canadian Heritage.
Read 22 tweets
Important 👉 This team is investigating bacterial quorum sensing peptides (QSPs) as metabolites that can contribute to #microbiome-driven disease processes👆They identified QSPs that selectively influence functionality of several types of neuronal #brain cells including microglia
Their abstract concludes that 👉 "Combined with our in-vivo studies indicating that these QSP are permeating the #intestinal wall, as well as the blood-brain barrier, our findings may open up a new field of diagnostic and therapeutic approaches for #neurological disorders."
Rob Moir describes a similar phenomenon in this interview, stating 👉 "#Vagus Nerve traffic may include #bacterial signaling molecules called quorum sensing molecules. In this sense microbes in the gut and microbes in the brain may be “talking...": microbeminded.com/2017/12/18/int…
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1/
I'm taking the #Coursera #Learning How to Learn course
bit.ly/1LqIUp4
This assignment is to teach others. I decided to make a giant thread for my coding community since you all give me so much.

#newDevCity
#100DaysOfCode
#CodeNewbie
#Study
#freeCodeCamp
@w3develops
@w3develops 2/
The course is teaching how learning happens. The course lessons are backed up by #neurological science. #Learning is not something only for the young, there are techniques that are easily obtainable to help you learn difficult subjects in any discipline.

#newDevCity
#Coursera
@w3develops 3/
"We ordinarily think of learning as something we do when we sit down to study a book. But actually, being able to learn more easily and deeply involves many important facets--including not only periods of focused concentration, but also periods of relaxation...

#newDevCity
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Incredibly important hypothesis piece published today 👉 “Proposed here is a theory that #microorganisms from within the #brain and elsewhere in the body contribute to the long-term #neurological deterioration characteristic of traumatic brain injury”: sciencedirect.com/science/articl…
From paper 👉 1. “First, since the normal human #brain is not sterile, but is host to a variety of microorganisms, blows to the #skull may dislodge them from their accustomed local environments, in which they have been living in quiet equilibrium with neighboring #brain cells”
2. “2nd, upon impact commensal #microbes already resident on surfaces of the nose, mouth + eyes, and potentially harmful organisms from the environment, may gain access to the #brain through the distal ends of the olfactory + optic #nerves or even a disrupted blood-brain barrier”
Read 6 tweets
Yet another team ties #neuroinflammation to persistent brain infection 👉 Here, RNA seq + western blot + antibody testing identified pegvirus inside the #brain cells of two patients who died from encephalitis (and not controls): folio.ca/u-of-a-scienti… ImageImage
Important that pegvirus acted as an intracelluar #pathogen (viral antigens were found inside glial cells + lymphocytes + astrocytes)☝️..w/ their presence in lymphocytes suggesting the “cells might serve as a Trojan horse for #viral infection of the brain parenchymal cells.” ImageImage
Also important is that detection of #pegvirus-antigen in the pre-transplantation bone marrow biopsy of one subject 👉 “indicated that this patient was infected at least 15 years before #neurological presentation, suggesting a period of viral latency.” Image
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Thread:

The 10 publications below provide scientific evidence that patients with #MECFS have #brain abnormalities in #neuroinflammation, #metabolism, #neurological connections and blood perfusion

#pwME suffer from #chronicillness

#pwME are #SickNotWeak
1. These studies “provide evidence of #neuroinflammation in #MECFS.. as well as evidence of the possible contribution of neuroinflammation to the pathophysiology of #MECFS

#pwME

jnm.snmjournals.org/content/55/6/9…
2. This Australian study found abnormalities in the #brain MRIs and peripheral Blood Pressure and Heart Rate in #MECFS patients including the Vasomotor centre, midbrain and hypothalamus

#pwME

sciencedirect.com/science/articl…
Read 14 tweets

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