Discover and read the best of Twitter Threads about #newcoronavirusvariant

Most recents (3)

A "Zwischen den Jahren" (between the years) update of the focal S:N501 build, with data from 25th Dec. ❄️

In 20B/501Y.V1 (SE England variant), we have new sequences from Australia, Israel, & Hong Kong:

1/5

#Newcoronavirusvariant #SARSCoV2 #COVID19

nextstrain.org/groups/neherla…
Filtering to just look at the Hong Kong & Israel samples, we can see that the 2 Hong Kong sequences sit further apart on the tree, indicating two separate introductions.

2/5

nextstrain.org/groups/neherla…
Similarly, the 3 Australian sequences also sit apart on the tree, indicating separate introductions.

3/5

nextstrain.org/groups/neherla…
Read 5 tweets
Merry Christmas! 🎄 The latest focal S:N501 build is now up.

Zooming in on 20B/501Y.V1 (SE England variant), we can see new sequences in Europe from the Netherlands.

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#Newcoronavirusvariant #SARSCoV2 #ChristmasCovid

nextstrain.org/groups/neherla…
Zooming in on this further, and switching to divergence view (showing mutations rather than time), we can see they share 1 unique mutation & then have 1 unique mutation each, suggesting 1 introduction, possibly from the UK, & onward transmission.

2/4

nextstrain.org/groups/neherla…
We can take a similar look at the Danish sequences. They too, share one unique mutation, & some further unique mutations, suggesting a single introduction & onward transmission.

3/4

nextstrain.org/groups/neherla…
Read 4 tweets
A case of the '#SouthAfrica' variant has been detected in the UK. There's also talk about a 501Y mutation in Wales.
It's getting confusing!

First: all 3 of these 501Y mutations are independent. It's appeared a few times, separately.

#Newcoronavirusvariant

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We can see this because the 3 variants (UK=1, Wales=2, SA=3) are not next to or inside each other in the tree below. In fact, we need to trace back to before March to find their common ancestors:

2/10

nextstrain.org/groups/neherla…
Are the UK and South Africa variants the same? No. See this thread for more info:

Critically, the SA variant does not have the 69/70 deletion we see in the UK variant.

3/10

Read 10 tweets

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