Discover and read the best of Twitter Threads about #nextseq

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Drawing Innovation: @illumina Super-Resolution Optics

Recently, $ILMN unveiled the NextSeq 2000, a mid-throughput sequencer w/ a ~2X reduction in operating costs ($/GB).

We think the upgrades inside the NextSeq 2000 may soon enable a $100 clinical-depth human #genome.

But how?
The cost savings come from (1) a new upfront #chemistry and (2) super-resolution optics. We think @illumina will use real-world customer data on the NextSeq 2000 to optimize 1 and 2, then possibly upgrade the #NovaSeq line.

illumina.com/systems/sequen…
I'm going to briefly (!) illustrate how #sequencing (*by synthesis*) works, walk through a farming analogy, then dive into some technical details. (Sources at the end)

Below is a general overview of a whole genome sequencing workflow (sample in, data out).
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