Discover and read the best of Twitter Threads about #nitazoxanide
Most recents (2)
☑️ REUSE OF DRUGS: THE ANTIHELMINTICS #NICLOSAMIDE AND #NITAZOXANIDE ARE POTENT ANTAGONISTS OF #TMEM16A 👉 THAT COMPLETELY BRONCHODILATE THE RESPIRATORY TRACT
ncbi.nlm.nih.gov/pmc/articles/P…
☑️ The pharmacology of the TMEM16A channel: therapeutic opportunities:
ncbi.nlm.nih.gov/pmc/articles/P…
☑️ The pharmacology of the TMEM16A channel: therapeutic opportunities:
The intracellular Ca-dependent Cl channel TMEM16A is a key regulator of vascular tone control and local blood flow.
°TMEM16A inhibitors have potential therapeutic uses👉 Asthma, COPD, Cystic Fibrosis, HTA/PAH, CVA, Overactive Bladder, Ca.
sciencedirect.com/science/articl…
°TMEM16A inhibitors have potential therapeutic uses👉 Asthma, COPD, Cystic Fibrosis, HTA/PAH, CVA, Overactive Bladder, Ca.
sciencedirect.com/science/articl…
°Pharmacological modulators👉 niflumic acid, flufenamic acid and mefenamic acid
💊 Reused 👉 Zafirlukast, Avermectins (Ivermectin), Niclosamide, Nitazoxanide, Cefarantine.
🌱Natural👉 Gallotannins, Evodiamine, Rutaecarpina, Luteolin, Galangina, Quercetin and Fisetin.
💊 Reused 👉 Zafirlukast, Avermectins (Ivermectin), Niclosamide, Nitazoxanide, Cefarantine.
🌱Natural👉 Gallotannins, Evodiamine, Rutaecarpina, Luteolin, Galangina, Quercetin and Fisetin.
There is no proven effective antiviral drug for the treatment of #SARSCoV2
Several compounds are suggested for Rx of #COVID19. Based on the available in vitro and clinical data, which one is your preferred Rx, if available? #MayoIDQ references follow...
Several compounds are suggested for Rx of #COVID19. Based on the available in vitro and clinical data, which one is your preferred Rx, if available? #MayoIDQ references follow...
1/
#Chloroquine
Anti-malaria
Several potential mechanisms: change in cell membrane pH, impairs viral fusion, interferes with glycosylation of viral proteins
#chloroquine and #redemsivir are active against SARS-COV2 in experimental models
doi.org/10.1038/s41422…
#Chloroquine
Anti-malaria
Several potential mechanisms: change in cell membrane pH, impairs viral fusion, interferes with glycosylation of viral proteins
#chloroquine and #redemsivir are active against SARS-COV2 in experimental models
doi.org/10.1038/s41422…
2/
#Hydroxychloroquine
- Analogue of chloroquine
- Anti inflammatory effect
Hydroxychloroquine was more potent than chloroquine against #SARS-CoV2 in vitro.
doi.org/10.1093/cid/ci…
#Hydroxychloroquine
- Analogue of chloroquine
- Anti inflammatory effect
Hydroxychloroquine was more potent than chloroquine against #SARS-CoV2 in vitro.
doi.org/10.1093/cid/ci…
