Discover and read the best of Twitter Threads about #noncoding
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OK, looks like Democracy is safe for now, and the push for reform is making headway. There's a long road ahead, but I'll take a brief timeout to report from @NYASciences's #Phenotypic2020 virtual conference.
First keynote was @OlgaTroyanskaya, presenting a range of tools for understanding #NonCoding genomic variants: DeepSEA, ExPecto, Fenrir...
Emphasizes that #ComplexDisease relies on networks and complex changes like #Aging, so we have to stop looking for 1->1 causal maps. Agree!
Emphasizes that #ComplexDisease relies on networks and complex changes like #Aging, so we have to stop looking for 1->1 causal maps. Agree!
Andrea Califano from @columbiacancer using combination of #HTS and #SingleCell Plate-Seq to look for cancer master regulators. VIPER identifies proteins whose regulatory effect impacts genes that distinguish cell states. Now running phase 1 trial!
