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Excess of vitamin B12 may be hazardous

1. Vitamin #B12 deficiency is known to cause anemia, peripheral neuropathy, dementia, psychosis and skin pigmentation. Vitamin B12 supplementation is needed in them, however, #vitaminB12 excess may have adverse effects on health and life.
2. In a recent study, >5500 people (mean age 53 years) were followed up for 8.2 years.
Those with high plasma vitamin B12 concentration had 25% higher risk of all-cause death.
The mechanism of increased death is unknown.
#MedTwitter #nurtition #vitamin
3. Older age, high blood pressure, poorer kidney function, as well as increased concentrations of liver enzymes, were positively associated with higher plasma concentrations of vitamin B12. So, these groups should be more cautious while taking vitamin B12 supplementation.
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