Discover and read the best of Twitter Threads about #om3
Most recents (2)
@mmillermd1 @PennCardiology @DLBHATTMD @UM_Cardiology @ASPCardio @nationallipid @BudoffMd @Medscape EPA effect on ASCVD in Japanese pts w/chronic CAD and EPA/AA ratios <0.4, on statins.
🐟EPA 1.8 gm (like JELIS)
🐟EPA baseline 46 ug/mL (JELIS, 96)
🐟All on statins, randomized to control or EPA, no blinding (like JELIS)
#aha22 1/ @AHAScience
🐟EPA 1.8 gm (like JELIS)
🐟EPA baseline 46 ug/mL (JELIS, 96)
🐟All on statins, randomized to control or EPA, no blinding (like JELIS)
#aha22 1/ @AHAScience
@mmillermd1 @PennCardiology @DLBHATTMD @UM_Cardiology @ASPCardio @nationallipid @BudoffMd @Medscape @AHAScience N=2506
🐟interesting drop out rate/protocol deviation, covid era?
🐟LDL-C baseline, similar to reduce it
🐟EPA median 46 ug/mL, higher than reduce it (26), lower than Jelis (96).
🐟hsCRP ~0.40
2/ #aha22
🐟interesting drop out rate/protocol deviation, covid era?
🐟LDL-C baseline, similar to reduce it
🐟EPA median 46 ug/mL, higher than reduce it (26), lower than Jelis (96).
🐟hsCRP ~0.40
2/ #aha22
@mmillermd1 @PennCardiology @DLBHATTMD @UM_Cardiology @ASPCardio @nationallipid @BudoffMd @Medscape @AHAScience 1,800 mg EPA
🐟46 ➡️ 145 ug/mL (26➡️150 ug/mL, reduce it)
🐟LDL-C, Trigs, HDL-C no change
🐟hsCRP went down in both
3/ #aha22
🐟46 ➡️ 145 ug/mL (26➡️150 ug/mL, reduce it)
🐟LDL-C, Trigs, HDL-C no change
🐟hsCRP went down in both
3/ #aha22
#ACC21
Nice work #STRENGTHTrial team! #OM3
First - primary endpoints not achieved. This is a sub-study.
Questions attempted to address:
- Could higher EPA explain favorable outcomes?
- Could DHA component have exactly counterbalanced benefits of EPA?
1/
Nice work #STRENGTHTrial team! #OM3
First - primary endpoints not achieved. This is a sub-study.
Questions attempted to address:
- Could higher EPA explain favorable outcomes?
- Could DHA component have exactly counterbalanced benefits of EPA?
1/
#ACC21
Recall #STRENGTHtrial randomized 13,000+. Similar MACE outcomes to #REDUCEIT.
STRENGTH sub-study looks at top tertile achieved EPA and DHA compared to corn oil.'
2/
Recall #STRENGTHtrial randomized 13,000+. Similar MACE outcomes to #REDUCEIT.
STRENGTH sub-study looks at top tertile achieved EPA and DHA compared to corn oil.'
2/
#ACC21
-Interesting that high intensity statin use in top tertile was 10% less than other tertiles and corn oil group.
-LDL-C was 7 mg/dL higher in top tertile group than next highest (T1)
-Achieved EPA (443%) and DHA (68%) is c/w with dose 2200 mg, 800 mg respectively
3/
-Interesting that high intensity statin use in top tertile was 10% less than other tertiles and corn oil group.
-LDL-C was 7 mg/dL higher in top tertile group than next highest (T1)
-Achieved EPA (443%) and DHA (68%) is c/w with dose 2200 mg, 800 mg respectively
3/
