Discover and read the best of Twitter Threads about #orf6

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prior infection isn't immunity,
it's a preexisting condition.

CoV damages ACE2 organs & immune system. It persists.

With ORF6 it suppresses immune response (by downregulating MHC1 & INFN)

With ORF8 it triggers T cell wear&tear.
(anergy, autoimmunity, less clearance, cancer)
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