Discover and read the best of Twitter Threads about #orthogroups
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🚨Exciting pre-print from the lab!👉"Pervasive evolution of tissue-specificity of ancestral genes differentially shaped vertebrates and insects". Deep comparative #transcriptomics across #bilateria by @FedeMantica et al @CRGenomica. 👀biorxiv.org/content/10.110…. Summary👇
How has tissue-specific gene expression evolved since the origin of bilaterian animals all the way to extant vertebrates and insects? To address this, we assembled a vast RNA-seq dataset covering 8 tissues and 20 species, generating 95 new RNA-seq samples for 15 species. 1/16 
Importantly, our study was entirely designed around a symmetric #phylogeny for the vertebrate and insect branches, allowing us to identify ancestral features but also parallel, convergent and divergent evolutionary trajectories between and within the two bilaterian lineages. 2/16
