Discover and read the best of Twitter Threads about #osteogenesisimperfecta
Most recents (2)
As the year ends, it's time once again to discuss some of the best clinical papers in the 🦴 #bone field in 2022!
A long 🧵
@Sandroppa @ECTS_science @larsfolkestad
A long 🧵
@Sandroppa @ECTS_science @larsfolkestad
Nr. 1: Supplemental #VitaminD and Incident #Fractures in Midlife and Older Adults @NEJM
No effect in the VITAL trial although confidence intervals do not exclude meaningful reduction in patients on osteoporosis meds or with fracture history
nejm.org/doi/full/10.10…
No effect in the VITAL trial although confidence intervals do not exclude meaningful reduction in patients on osteoporosis meds or with fracture history
nejm.org/doi/full/10.10…
#VitaminD Deficiency Increases Mortality Risk in the UK Biobank
A Nonlinear Mendelian Randomization Study
Risk increased steeply < 50 nmol/L and was greater with genetic than phenotypic vitamin D deficiency
@AnnalsofIM
acpjournals.org/doi/10.7326/M2…
A Nonlinear Mendelian Randomization Study
Risk increased steeply < 50 nmol/L and was greater with genetic than phenotypic vitamin D deficiency
@AnnalsofIM
acpjournals.org/doi/10.7326/M2…
In discussing therapies for skeletal dysplasia, @mikebbober highlights these are a heterogeneous group of unique disorders #HotTopicsNeo2020 #neoEBM 
Best-practice guidelines for delivery and evaluation of patients with skeletal dysplasia ajog.org/article/S0002-… and skeletaldysplasia.org
Trial for a new enzyme-replacement therapy (ENB-0040) for severe hypophosphatasia: nejm.org/doi/full/10.10…
