Discover and read the best of Twitter Threads about #pancreaticslices
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#1 Excited to share the final aim of my PhD thesis, now out in @NatureComms. Another fantastic collaborative effort between @DiabetesnPOD @Diabetes_DRI @umiamimedicine @PLID_Info @UF @TheHpap @HIRN_CC @ADA_DiabetesPro #pancreaticslices #pancreas #T1D #T2D nature.com/articles/s4146…
#2 First of all what are human pancreatic tissue slices (HPS)? these are 120-130micron thick tissue slices from a human pancreas donated for research. HPS have been used previously to study beta-cell physiology but owing to difficulties they were difficult to culture.
#3 Why is it important to culture them? culturing HPS allows for a new method to study the human pancreas while maintaining human pancreatic cytoarchitecture. This makes the long term culture of HPS a useful model system to study T1D, T2D, metabolic stress + pancreas-physiology.
