Discover and read the best of Twitter Threads about #pancsm

Most recents (6)

In May 2019, Dr. @rschilsky & I co-chaired the #AAADV19 Workshop Plenary Session "Decentralized #ClinicalTrials: The Future is Now." An incredible group of panelists from academia, industry, govt, & patient #advocacy 👇discussed the rationale, challenges, & opportunities of DCTs. Image
No one knew yet that the #COVID19 #pandemic was just around the corner. In Mar 2020, FDA released a guidance on conduct of #clinicaltrials during the pandemic: fda.gov/media/136238/d…, & colleagues wrote about the impact on #OncTwitter trials: ncbi.nlm.nih.gov/pmc/articles/P…. /2
FDA has now released a draft guidance on decentralized #clinicaltrials for drugs, biological products, & devices covering #telehealth, remote assessments, consent, shipping of IP, & more: fda.gov/media/167696/d…. #MedTwitter #regulatory #drugdevelopment Image
Read 5 tweets
1/12 #TumorBoardTuesday
Thurs 10/12/21 Case🎀
@ShaalanBeg @CancerCommons present a case of #PancreaticCancer that challenges us to🤔about cell signaling & mol bio➡️better outcomes.

📚We captured as much of the chat as we could:
twitter.com/i/events/14479…
#PanCan #KRAS #OncTwitter
2/12 #TumorBoardTuesday
Thurs Case🎀

Take🏠messages:
We discussed #PancreaticCancer & specific #KRAS mut
✅All KRAS muts aren’t ≠
✅KRAS G12R➡️⬆️autophagy
✅Autophagy= tumor can♻️cell components ➡️resistance
✅MEKi + autophagy inhib= strat for G12R
✅Repeat NGS on prog is🗝️!
3/12
#TumorBoardTuesday
Thursday Case🎀

👉👉 Don’t forget to pick up 🆓 #CME credit by answering 3 quick ❓
Here is the post-test 🔗: bit.ly/3Bzgply

ALL CME 🔗: integrityce.com/tbt
Read 15 tweets
Here it is: #LateBreakingAbstract at #ASTRO20 SS19 available to view now! Early analysis of trial (NCT03340974) using high-dose SBRT with avasopasem (GC4419) in #PancreaticCancer #PancSM #ASTRO20 Thread👇
This trial tried to address an unmet need for a specific group of #PancreaticCancer #PancSM patients whose disease had not progressed but remained unresectable after chemotherapy. #ASTRO20 @ACKoongMDPhD
Patients would be enrolled on the trial after finishing a minimum of 3 months of standard-of-care chemotherapy. They would receive SBRT with Avasopasem or a placebo control just prior to each SBRT treatment. #ASTRO20
Read 14 tweets
One day late, but wanted to summarize #PancreaticCancer #PancSM talks from yesterday’s #ASTRO20 session on hypofractionation in GI Cancers before spill the beans on my study... 1/9
@MikeChoungMD gave a great talk on the @UMiami experience with #MRLinac for #PancreaticCancer #PancSM. This is a great technology that allows #RadOnc to replan the treatment each day based on the anatomy of the nearby bowel. #ASTRO20 2/9
In this study on #MRLinac, they showed that they can safely deliver ablative doses (about 50Gy/5 fractions) with less than 2% acute and late GI tox. #ASTRO20 3/9
Read 9 tweets
Bird’s-eye view 👁 on what to look out for @WCGIC #WorldGI2020.
Opening remarks on important data 📺 @myESMO - by Dr. Eric Van Cutsem @UZLeuven.
🟩Good to see more #PrecisionMedicine🧬
🟥#Immunotherapy #Immuno-#oncology
🟦TNT & other chemo strategies
@Annals_Oncology #OncoAlert
🆕#ctDNA #liquidbiopsies 🩸🧬
👀 👇🏾at the number of #clinicaltrials cropping up in this space‼️
🇦🇺DYNAMIC-II
🇦🇺DYNAMIC-III
🇺🇸COBRA @NRGonc
🇺🇸BESPOKE
🇺🇸@SU2C
🇯🇵 CIRCULATE
🌎COLUMBIA
🇮🇹🇪🇸PEGASYS
🇬🇧TRACC
🇩🇪CIRCULATE
🇫🇷crEATE
🇩🇰IMPROVE-IT
We have 2🇺🇸studies open. #CRCSM #WorldGI2020
#WORLDGI2020 This is 🆒 ☢️ 32-P EUS-guided implantation in #pancreascancer #PANCSM @myESMO @WCGIC @Annals_Oncology.

Still miles to go. OS median of 16 months pointing again to the systemic nature of disease. Need to piggyback these local approaches to better systemic. #OncoAlert
Read 55 tweets
THREAD
1/
Eponyms are falling out of favor in medicine. They aren't descriptive and essentially require twice the memory space to recall both the name & the associated term.

But pancreaticoduodenectomy doesn't exactly roll off the tongue so I suspect the Whipple is here to stay.
2/
Dr. Allen Whipple was a pioneering surgeon whose contributions to the field also include a still-relevant understanding of insulinomas (see also: Whipple's triad).

Still his incisive approach to the pancreas, small intestine, and bile ducts remains why he is best-remembered
3/
I have no operative skills myself so I like to describe that the Whipple-performing surgeon does to the upper abdomen what Picasso did to faces: radical rearrangements that, in the end, bare some vague semblance to the original orientation of features.
Read 10 tweets

Related hashtags

Did Thread Reader help you today?

Support us! We are indie developers!


This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!