Discover and read the best of Twitter Threads about #pango

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Parece que tenemos una nueva variante del covid made in Peru. Se llama omicron DJ.1, ha estado creciendo en las últimas semanas y podría estar detrás de la ola actual de casos.🧵

1/n
Este análisis se basa en el último set de #datosabiertos disponibles para Perú, generado por lxs colegas de @INS_Peru y compartidos en @GISAID. Llegan hasta la última semana octubre y se suben nuevas secuencias todas las semanas.

2/
Hace unos días les hablé de las múltiples variantes omicrones que han aparecido: Linajes distintos entre sí pero que convergen en las mismas mutaciones de la proteína spike que se asocian a unión de anticuerpos y afinidad por el receptor ACE2.

3/
Read 17 tweets
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (15-DAY TRENDS):

46.66% BA.2.12.1**,
23.33% BA.5^^,
12.15% BA.4^^,
7.64% BA.2,
4.24% BA.5.1^^,
1.29% BA.2.9 and
1.17% unassigned

**S:L452Q; ^^S:L452R/F486V

Tracker: tinyurl.com/mryj4uu7
#OmicronUpdates 6/27/22
#OmicronVariantUpdates #UnitedStates 06/27/22

Top 5 lineages:
BA.2.12.1, ⬇️ (Spike: L452Q)
BA.5, ⬆️ (Spike: L452R)
BA.4 ⬆️ (Spike: L452R)
BA.2 ⬇️
BA.5.1 ⬆️👀 (Lineage prevalent in #Portugal)

* includes recently designated BA.2.x.y and undesignated BA.2s
#SARSCoV2 lineages in USA (#15DayTrends)

Circulating #BA5*/#BA4* sub-lineages:
BA.5, BA.4.1, BA.5.2.1, BA.5.1, BA.4, BA.5.2, BA.5.3.1, BE.1, BF.1, BA.5.3

Assignments via: #Nextclade #PANGO - clades.nextclade.org
Read 13 tweets
#OmicronUpdates #NewLineagesAlert

BA.1.22 -Prevalent in #Peru
BA.2.17 - #Vietnam and others
BA.2.18 - #UK/#Ireland
BA.2.19 -#Germany
XU - BA.1*/BA.2 recombinant - #Japan/#Canada/#India

(BA -alias of B.1.1.529)

#PANGO issues: #520, #522, #528, #529, #535
These are new PANGO designations

Key mutations:

BA.2.17 - ORF3a:D173Y
BA.2.18 - S:K417T
BA.2.19 - ORF1a:T333M

more to follow ..... will update key mutational differences and transmission advantage (if any)

Other designations are in 🧵:
#OmicronUpdates #NewLineagesAlert

BA.2.22 prevalent in #UnitedKingdom
BA.2.21 prevalent in #USA/#Canada
BA.2.20 prevalent in #Canada

(BA alias of B.1.1.529)

PANGO issues: #547 #562 #544
Read 5 tweets
New #PANGO designations - BA.2.*

BA.2.4Alias of B.1.1.529.2.4, #Singapore lineage

BA.2.5Alias of B.1.1.529.2.5, lineage in #Portugal and other countries

BA.2.6Alias of B.1.1.529.2.6, lineage in #France and other countries

BA.2.7Alias of B.1.1.529.2.7, #USA lineage ImageImage
These are new designations - branching from the BA.2 subvariant

more to follow ..... will update key mutational differences and transmission advantage (if any)
BA.2.4 (aka B.1.1.529.2.4) | prevalent in Singapore

Key mutation: ORF6:M58K

COV-spectrum predicts a growth advantage of 14% over BA.2 and 46% over BA.1.1 in #Singapore

BA.2 and BA.1.1 are currently the dominant lineages in circulation in Singapore Image
Read 29 tweets

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