Discover and read the best of Twitter Threads about #pathogens

Most recents (24)

"#Ritual. #Narrative. #Context. #TemporalStability. In short, everything missing from the connected isolation of #DigitalDisconnectivity is the antidote to its corrosion of community." -- Nathan Gardels greeneracresvaluenetwork.wordpress.com/2022/04/25/dai…
What pricing the value of a combat death reveals about war - The Blind Spot
the-blindspot.com/what-pricing-t…
#CombatDeath, #CostOfWar, #CombatantValue
Read 13 tweets
1/20 #LongThread/continuation but worth it! Again sorry for type-errors (I am glad that I survived it) Excerpt/Quote about Viral persistence & consequences to reactivation other pathogens! @microbeminded2 ♥️💐💙

“To me it is, yes (viral persistence as simplest explanation)…
2. because then it can start to explain so many of the other things that are measured. So we could explain some of the #autoantibody production by persistence of the virus, we can certainly explain how other pathogens may themselves be reactivated.
3. That’s definitely I think a trend that haven’t described as much … but all of us are seated with other organisms. Other pathogens that are #herpes viruses, Epstein-Barr, CytomegaloVirus but also sometimes for example #toxoplasma is a parasite that one third of the world …
Read 20 tweets
Russian Slow Advance Faces Ukrainian Virtual Victories: 21th Day Of Military Operations In #Ukraine | Mar 17
-The recent days of the Russian mil ops in Ukraine were marked by significant successes of the joint forces of the Russian Fed, the DPR and the LPR
archive.vn/GwLzL
The DPR units with the close Russian support continue to move forward in the city of #Mariupol. The fighting has already approached the Azovstal Metallurgical Plant.
https://southfront'DOT'org/wp-content/uploads/video/17.03.2022_IMR_Ukraine.mp4
Read 4 tweets
Russia claims #US wanted to spread infectious #diseases via #biolabs in #Ukraine | Mar 18
-Russia’s Der Min accused the US of developing infectious diseases in biolabs in Ukraine with the aim of spreading them to Russia disguised as '#natural outbreaks.'
v.aa.com.tr/2538852
'#Pentagon funded' #Biolabs near #Russian borders.
#OMG Boris @BorisJohnson
#Pentagon funded #Novichok is made in #USA and developed further in #Salisbury.
Patent No: US 9,132,135 B2.
"Methods of a treatment of #organo-#phosphorus #poison agents" issued in Sep. 2015, Pat. filed in 2008.
Read 16 tweets
This is the most straightforward explanation for chronic symptoms in at least a subset of #LongCovid patients. Partly b/c if the #virus is still present its activity can directly contribute to other phenomena also being documented in LongCovid
2/ Persistence of #SARS-CoV-2 in tissue could lead to shedding of spike protein into blood, which can catalyze the ongoing formation of microclots and hyperactivated platelets
3/ Persistence of SARS-CoV-2 can lead to ongoing downregulation of interferon and/or T cell signaling by the virus, creating an optimal atmosphere for activation of EBV or other #pathogens normally controlled by such immunity
Read 10 tweets
Who's ready for another jab in March? Roll up your sleeve (again) for #Pfizer 1.1:

CEO Albert Bourla, Jan 10, 2022: "And we know that the 3, the 2-dose[s] of the #vaccine, offer very limited protection, if any."

#4IR #BiotechEconomy #GeneEditing #mRNA #Crispr

Thread 👇
Bourla con't: "The 3 doses w/ the #booster, they offer reasonable protection against hospitalization & deaths... Now, we are working on a new version of our vaccine, the 1.1 [] that will cover #Omicron as well."

Bourla: "... we are waiting to have the final results. The vaccine will be ready in March, & [] we'll be able to produce it massively."

Yahoo: "I want to quickly talk about the #kids... under 5... the company has said that it's going to need to be a 3-dose vaccine..."
#biotech
Read 6 tweets
@kimisgubbed @VirusesImmunity @KaminskiMed @Be_Kinderr @jenbrea @ahandvanish Hey! Well hypoxic tissue cld lead to lower O2 extraction, & infected tissue is often hypoxic. Most intracellular pathogens hijack metabolism of cells they infect & “push” host mitochondrial metabolism to anerobic glycolysis (O2 not being used for OXPHOS): ij.hapres.com/htmls/IJ_1341_…
@kimisgubbed @VirusesImmunity @KaminskiMed @Be_Kinderr @jenbrea @ahandvanish 2/ In fact many intracellular #pathogens either directly or indirectly enhance hypoxia inducible factor (HIF-1) stability. HIF-1 is a key glycolytic regulator/transcription factor whose stability reduces reliance on OXPHOS by initiating glycolytic #metabolism
@kimisgubbed @VirusesImmunity @KaminskiMed @Be_Kinderr @jenbrea @ahandvanish 3/ With that in mind @VirusesImmunity, it was interesting that in your brain organoid model, you showed SARS-CoV-2 capable of infecting neurons, where it induced a locally hypoxic environment as measured by staining for HIF-1 alpha: pubmed.ncbi.nlm.nih.gov/33433624/
Read 11 tweets
"I am convinced that immunizing young #children [] will lead to a tsunami of #autoimmune diseases." - Dr Geert Vanden Bossche, virologist

Don't think for 1 sec. that the #pharmaceutical industry is unaware of the implications as outlined by V. Bossche.

#Immunity-As-A-Service
"We cannot, we should not, under NO condition, vaccinate any child." - Dr Geert Vanden Bossche, #virologist

COVID-19 Vaccine Risks in #children - Geert Vanden Bossche speaks

Full presentation:

April 10, 2019: "Why Are #Autoimmune Diseases on the Rise?"

"It’s not so much our cleanliness but our increasingly #industrial lifestyle that is blocking the intake of these important #microorganisms."

elemental.medium.com/autoimmunity-i…
Read 7 tweets
2/12/21: Newsweek: "Miraculous #mRNA #Vaccines are only the Beginning"

#mRNA vaccines offer "an early look at how the miraculous tools of the #genetics #revolution will transform our #healthcare & our world over the coming years."

#4IR #biotech

newsweek.com/miraculous-mrn…
"...our Promethean technologies, our moment of triumph could set us on a path to disaster. Of all the species that have ever lived, our single group of hominins now has the capacity to remake all of #biology."

#GeneEditing #4IR #Biotech
The new #vaccines are perfect early examples of this "godlike #technology." ... This approach will soon create a whole new platform for fighting cancers & other diseases, as well as for providing enhancements even more profound than #vaccination."

Human #Experiment w/ #mRNA
Read 11 tweets
2/12/21: Newsweek: "Miraculous #mRNA #Vaccines are only the Beginning"

#mRNA vaccines offer "an early look at how the miraculous tools of the #genetics #revolution will transform our #healthcare & our world over the coming years."

#4IR #biotech

newsweek.com/miraculous-mrn…
"...our Promethean technologies, our moment of triumph could set us on a path to disaster. Of all the species that have ever lived, our single group of hominins now has the capacity to remake all of #biology."

#GeneEditing #4IR #Biotech
The new #vaccines are perfect early examples of this "godlike #technology." ... This approach will soon create a whole new platform for fighting cancers & other diseases, as well as for providing enhancements even more profound than #vaccination."

Human #Experiment w/ #mRNA
Read 10 tweets
Daily Bookmarks to GAVNet 07/09/2021 greeneracresvaluenetwork.wordpress.com/2021/07/09/dai…
WHAT IS BITCOIN?



#tutorial #bitcoin
After the pandemic: perspectives on the future trajectory of COVID-19

nature.com/articles/s4158…

#PostPandemic #COVID19 #FutureTrajectory
Read 8 tweets
@MBVanElzakker and I are excited that our new paper on biological factors that may contribute to the development of LongCovid/PASC was published today: frontiersin.org/articles/10.33…
2/ The paper details mechanisms by which RNA #viruses beyond just #SARS-CoV-2 have be connected to long-term health consequences.
3/ It also reviews literature on acute #COVID-19 and other virus-initiated chronic syndromes such as post-#Ebola syndrome or #ME/CFS to discuss different scenarios for #LongCovid/#PASC symptom development.
Read 10 tweets
Thanks @DrDavidACox for interviewing me for this article on #LongCovid. There’s also great info in the article on research showing #viral RNA in the brains of patients w/ post-SARS syndrome, and viral reservoirs in patients w/ post-Ebola Syndrome: bbc.com/future/article…
2/ The article reads: “Amy Proal, a microbiologist who runs the @polybioRF which studies the causes of chronic inflammatory diseases, believes that small amounts of #pathogens that linger beyond the reach of the immune system in remote pockets of the body...
3/ “...known as reservoirs or anatomical sanctuaries, are at least partially responsible for a whole range of post-infectious syndromes. This includes long #Covid, but also a number of mysterious illnesses which have puzzled scientists for decades, such as chronic Lyme disease..
Read 14 tweets
2019: "a person's average micro-plastic consumption is between 70,000-121,000 particles per yr & rising for those who drank bottled water closer to 100,000."

Imagine plastic inhalation/consumption for those wearing #masks for past yr. #VirtueSignalling

scmp.com/news/china/sci…
"Disposable face masks (single use masks) are produced from polymers such as #polypropylene, #polyurethane, #polyacrylonitrile, #polystyrene, #polycarbonate, #polyethylene, or #polyester (Potluri and Needham, 2005)."

They shed. Plastic is inhaled/ingested. By adults & #children.
"This new emergence of #facemasks as environmental litter both in the terrestrial & aquatic environment is a piece of evidence that the global pandemic has not in any way reduced the challenge of increasing #plastic #pollution in the environment."

#Biodiversity #Ecology
Read 8 tweets
Important paper 👉 A team in Tokyo took RNA-seq data from the Genomic-#Tissue Expression Project: a public resource created to study tissue-specific gene expression/regulation from 54 tissue types collected from 1000+ healthy individuals at autopsy: bmcbiol.biomedcentral.com/articles/10.11…
2/ They successfully identified 39 viral species in at least one tissue (tissue types included #brain, pituitary, esophagus, thyroid, #heart, breast, lung, kidney, adrenal gland, prostate, #nerve, adipose tissue, blood vessel, ovary, uterus etc)
3/ Viruses identified in the various tissue samples included EBV, HSV-1, Varicella, CMV, HHV6-A/B, HHV-7, HCV, HPV, adeno-associated virus...and 16 RNA #viruses including Respiratory syncytial virus (RSV), Parainfluenza Virus 3..
Read 12 tweets
This is an incredibly important preprint to inform #LongCovid. Among many analyses, the team recruited 4 patients w/ prolonged + recurrent olfactory function loss after #COVID-19 (time from first COVID-19 symptoms to inclusion ranged from 110-196 days): biorxiv.org/content/10.110… Image
2/ None of these patients had detectable COVID-19 #RNA in nasopharyngeal samples by routine diagnosis (RT-qPCR). However, ALL patients had detectable COVID-19 RNA in samples obtained from their olfactory mucosa (confirmed with aRT-qPCR SYBR technique)
3/ Three of the patients had a high COVID-19 #viral load in the olfactory mucosa. Immunostaining additionally revealed the presence of COVID-19 antigens in 3 out of 4 patients. Based on that and related findings the team concluded...
Read 8 tweets
@jenbrea Hey! So I'm getting to the point where I could write a long paper about potential overlapping connections b/t #Alzheimer's and #MECFS, but I'll summarize a few top trends in this thread! First, I brainstormed often on topic with the late Rob Moir
@jenbrea 2/ Rob’s research (done w/ Rudy Tanzi + Will Eimer at Harvard) forms the core of a potential ongoing paradigm shift in Alzheimer’s - namely that #amyloid beta may be an antimicrobial peptide that forms in response to pathogens in #brain tissue: pubmed.ncbi.nlm.nih.gov/30001512/
@jenbrea 3/ To better understand that research, read this #interview I did with Rob before he passed away last year from glioblastoma. Key to ME/CFS is his work indicates that amyloid may form in response to herpesviruses like HSV1 in the Alzheimer’s brain: microbeminded.com/2017/12/18/int…
Read 14 tweets
This interesting study found that skeletal #muscle cells of #ME/CFS patients showed a decrease in oxidative phosphorylation (a metabolic pathway used by #mitochondria to generate #energy). In simple terms, that caused the cells to have a dysregulated #metabolism.
2/ Not mentioned in the paper, but important to consider, is that most well-studied #viral + bacterial #pathogens “hijack” the metabolism of the cells they infect in a manner that can result in decreased oxidative phosphorylation (or similar changes in cell energy pathways).
3/ In simples terms, these #pathogens “hijack” cell metabolism to “pull” substrates out of the human mitochondrial energy pathways...and use the substrates (lipids, fatty acids, amino acids) for their own #nutritional and replication purposes!
Read 6 tweets
@kayhoflander @mikeparson @TeamParsonMO @Mikelkehoe @JayAshcroftMO @FitzpatrickMO @Eric_Schmitt @TeamSchmittMO @s_webber @JasonKander @KDHE @VFWHQ @Mizzou @muhealth @WUSTL @BluebirdsofMO @collhistgarden @mizzouatheart @PhyllisMarion7 @sarahkendzior @CoriBush @GovJayNixon @KCStar @stltoday @KCTV5 @clairecmc @MO_HouseDems At this juncture, it’s clear to explain
an old saw from Mike Parson’s campaign:
random rural yard signs to
applaud Mike’s designs to
continue his post-Greitens reign.
In this specimen Parson would take in
uninformed voters in County Macon. 1/2 🔥 #mogov 🗳️
Image
@kayhoflander @mikeparson @TeamParsonMO @Mikelkehoe @JayAshcroftMO @FitzpatrickMO @Eric_Schmitt @TeamSchmittMO @s_webber @JasonKander @KDHE @VFWHQ @Mizzou @muhealth @WUSTL @BluebirdsofMO @collhistgarden @mizzouatheart @PhyllisMarion7 @sarahkendzior @CoriBush @GovJayNixon @KCStar @stltoday @KCTV5 @clairecmc @MO_HouseDems The reality, though: far more grim
as school districts may soon sink, not swim
in each piteous scene
of a mass quarantine as
new cases exceed counties’ brim.
Yet the venue’s the same:
still in Macon. Why no
mask mandate? Parson’s mistaken.
2/2 🔥 #mogov 🗳️
@kayhoflander @mikeparson @TeamParsonMO @Mikelkehoe @JayAshcroftMO @FitzpatrickMO @Eric_Schmitt @TeamSchmittMO @s_webber @JasonKander @KDHE @VFWHQ @Mizzou @muhealth @WUSTL @BluebirdsofMO @collhistgarden @mizzouatheart @PhyllisMarion7 @sarahkendzior @CoriBush @GovJayNixon @KCStar @stltoday @KCTV5 @clairecmc @MO_HouseDems Yes; thank goodness the
National Guard, unlike Mike,
at this moment works hard
citizens to protect.
Parson’s lies we reject,
evidenced by his COVID scorecard.
Folks still ask: why no #MaskUp
mandate? Parson’s post outweighs
the #ShowMe State.

🔥 #mogov 🗳️
Read 347 tweets
Read 354 tweets
Read 354 tweets
#Haemolysis data indicates that #disruption of host cell #membranes by rotating #flagella is physically possible, despite what previously published measurements with firing gold nanobeads at tissue cultures tells us.

[Pls read the paper for the more complex story with E.coli]
But what if #flagella did penetrate host cell #membranes? What might that mean?
Well, in vitro at least, #Ecoli and #Salmonella #flagella can enhance #actin #polymerization rates. Interactions with #Cofilin-1 (CFL) had an additive effect... Actin polymerisation rates with flagella from E. coli (H6, H
Read 8 tweets

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