Discover and read the best of Twitter Threads about #phosphoproteomics
Most recents (1)
Mass spec-based #phosphoproteomics has revolutionized the systems-wide analysis of phosphorylation. A 🧵 of some great developments for global analysis of kinase/phosphatase regulation and substrate phosphorylation…1/23
First step is enrichment. PAC, IMAC and MOAC are the most popular. In 1986, Andersson and Porath were one of the first to show that Fe3+ could bind phosphoamino acids sciencedirect.com/science/articl…
In 1997, Ikeguchi & Nakamura first used TiO2 2/23 link.springer.com/article/10.211…
In 1997, Ikeguchi & Nakamura first used TiO2 2/23 link.springer.com/article/10.211…
In 2002, Forest White and co-workers further developed IMAC to identify 383 phosphosites from yeast representing one of the early phosphoproteome analyses. 3/23 nature.com/articles/nbt03…
