Discover and read the best of Twitter Threads about #pku
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It’s been said that we can design and program bacteria like we can program a computer with code – however programming is only the beginning of what it takes to advance live bacterial therapeutics to patients – a 🧵 on how it is done (1/)
Today we @synlogic_tx show what it means to bring the power of synthetic biology to medicine, announcing clinical POC for our PKU program and showing the ability iterate and maximize activity in Synthetic Biotics #synbio (2/)
investor.synlogictx.com/news-releases/…
investor.synlogictx.com/news-releases/…
Using synthetic biology, we are able to apply engineering principles to design bacteria to perform specific biological functions – such as the metabolism of phenylalanine to potentially treat #PKU (3/)
ACM #Multimedia 2021: Skeleton-Contrastive 3D Action Representation Learning w/ @fmthoker, @doughty_hazel: arxiv.org/abs/2108.03656 We learn invariances to multiple #skeleton representations and introduce various skeleton augmentations via noise contrastive estimation 1/n 
Contribution I: leverage multiple input-representations of #3D-#skeleton sequences. Our inter-skeleton contrast learns from a pair of representations in a cross-contrastive fashion. Enriches the sparse input space and focuses on the high-level semantics of the skeleton data. 2/n
Contribution II: three skeleton-specific #augmentations for generating positive pairs which encourage the model to focus on the spatio- temporal #dynamics of skeleton-based @action sequences, ignoring confounding factors such as viewpoint and exact joint positions. 3/n
