Discover and read the best of Twitter Threads about #plasmid

Most recents (3)

26/50 The detected "SV40 promoter with 72bps indel" is a "nuclear localization signal" that means either the #plasmid or one of its expressed proteins can be transported into host cell nuclei,...
27/50 ...where the host DNA is found, creating an open question of whether host DNA interaction will occur and to what effect e.g. integration with human DNA. anandamide.substack.com/p/sequencing-o…
28/50 Potential effects of plasmid #contamination in vivo? Notable, five chemistry professors from German universities have been studying #Pfizer #BionTech's covid vaccine. They addressed some questions to the company. Where does the gray tone come from?
berliner-zeitung.de/gesundheit-oek…
Read 29 tweets
Emergence of extensively drug-resistant (XDR) and multidrug-resistant (MDR) #Shigella flexneri serotype 2a associated with #sexual transmission among men who have sex with men (MSM), in #England: a descriptive epidemiological study
1/6
👇
thelancet.com/journals/lanin…
In this study, authors report the emergence and sustained transmission of #XDR and #MDR strains of S flexneri among among MSM, harbouring plasmid-encoded blaCTX-M-27, in England since September, 2021.

There were clinically severe cases, including hospitalisations.
2/6
Comparison to the XDR S. sonnei outbreak revealed epidemiological and #plasmid similarities and provided support for horizontal acquisition events in a community transmitting infection.
3/6
Read 6 tweets
Check out our new paper by @smartinezarbas et al. about #CRISPR mediated interactions within a wastewater #microbiome in @NatureMicrobiol! Exciting collaboration between @uni_lu @TGen @IUBloomington @isbsci @KU_Leuven. Funding by @FnrLux
nature.com/articles/s4156…

A 🧵👇

1/9
In parallel with recent work of @mhe345 @NatureComms nature.com/articles/s4146…, we explored the roles of #plasmids and #phages within a wastewater treatment plant microbial community, using longitudinal integrated #omics data 2/9
We identified 31 bacterial MAGs with complete #CRISPR-Cas systems from the 14-months data set. These MAGs served as the basis for downstream population-level analyses of #CRISPR interactions 3/9
Read 9 tweets

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