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As business from around the world meet at the @OceanCouncil Sustainable Ocean Summit 🌊 to discuss the #ocean, #climate and #biodiversity, #PLOSBiology is proud to announce our new collection of articles on #OceanSolutions for a sustainable, healthy and inclusive future 🧵1/11
Collection guest editors Nancy Knowlton @SeaCitizens and Emanuele Di Lorenzo @manu_ocean outline their vision for the collection in their Editorial #OceanSolutions 🧵2/11
plos.io/3Tvazu5
plos.io/3Tvazu5
In their Perspective, @jenniferjacquet and Daniel Pauly argue that the current definition of ‘#sustainable fisheries’ should be reimagined to minimize exploitation and prioritize small-scale artisanal and subsistence fishing #OceanSolutions 🧵3/11
plos.io/3MBQfFf
plos.io/3MBQfFf
Most important sentences of our most recent peer-reviewed publication :
Every case of monkeypox infection should be treated with the same attention and sense of urgency as the ones now in European countries and North America.
Every case of monkeypox infection should be treated with the same attention and sense of urgency as the ones now in European countries and North America.
The entire epidemic of hMPXV regardless of the location needs to be halted, not just this Northern hemisphere outbreak.
We hope that the world provides the funding and focus for effective regional and global public health surveillance for emerging and re-emerging threats.
We hope that the world provides the funding and focus for effective regional and global public health surveillance for emerging and re-emerging threats.
By supporting a non-discriminatory and non-stigmatizing classification, we can encourage African and other researchers in low- and middle-income countries (LMICs) to advance genomic surveillance, share sequence data, and minimize negative impacts.
If pleiotropy is simply when one mutation influences many traits, how come so many nuanced definitions of it exist? 1/17 
One answer is that it is not easy to count traits. For example, consider cell circumference and area. Are those two traits or one? For a harder example, consider the mutation that makes tomatoes ripen uniformly and also makes them taste bad. Sounds like pleiotropy, right? 2/17
But is it fair to call this tomato mutation pleiotropic if its singular effect is to reduce function of a transcription factor that promotes chloroplast development, which in turn affects both coloration and sugar accumulation? (This is called ‘vertical pleiotropy’). 3/17
#PLOSBiology: Single-cell transcriptomics of the naked mole-rat reveals unexpected features of mammalian ... dx.plos.org/10.1371/journa…
Our article describing the immune system of the long-lived and cancer-resistant naked mole-rat published @PLOSBiology today. A brief(ish) thread 👇
Our article describing the immune system of the long-lived and cancer-resistant naked mole-rat published @PLOSBiology today. A brief(ish) thread 👇
The naked mole-rat is long-lived (~30y!) and doesn't seem to get cancer very often. But almost nothing is known about its immune system. In this study we used single-cell RNA sequencing of the blood and spleen to remedy that. Needless to say, we found some weird stuff....
The naked mole-rat has half the number of lymphoid cells found in the laboratory mouse (44% vs 90%). The major difference here comes from B-cells (14% vs 59%). The naked mole-rat makes up for this with more granulocytes and APCs.
