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Andy Feinberg has written a review about #epigenetics in @NEJM.
Unfortunately, it’s damaging to the field of human epigenetics research.
The Key Role of Epigenetics in Human Disease Prevention and Mitigation
nejm.org/doi/full/10.10…
Unfortunately, it’s damaging to the field of human epigenetics research.
The Key Role of Epigenetics in Human Disease Prevention and Mitigation
nejm.org/doi/full/10.10…
A couple of historical inaccuracies to start. Waddington was saying the opposite – cell fate (the cellular event in epigenesis) is probabilistic, not deterministic. The major point he was making was that genes have a role in influencing epigenesis, a major argument at the time 
Waddington did not ignore environment at all. In fact, he treated Drosophila larvae with heat/ether to see whether he could influence cell fate. He considered the epigenetic landscape (cell fate) potentially modifiable by environment and genetic variation, see next image
