Discover and read the best of Twitter Threads about #pprom

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Can you monitor maternal & fetal safety in clinical trials in pregnancy? Now you can, with #MFAET version 1.0 published this week @ISPDHQ
The 12 maternal & 19 fetal Adverse Event definitions are adopted by @MedDRAMSSO
obgyn.onlinelibrary.wiley.com/doi/10.1002/pd…
ucl.ac.uk/womens-health/…
1/ Researchers @ucl @UCL_IfWH @UCLHresearch have developed a standard terminology for safety monitoring for pregnant women and their fetuses during development of drugs for pregnancy. #Pregnancy #AdverseEvents #MaternalSafety #fetus #MedDRA #MFAET
ucl.ac.uk/news/2021/oct/…
2/ Adverse Event (AE) monitoring is central to assess therapeutic safety. The lack of an AE framework in pregnancy trials severely limits understanding risks in pregnant women. #MFAET was developed by international consensus of healthcare professionals & patient public groups.
Read 15 tweets
Sadly, just over a week ago we lost our twin boys

Teddy came and went from this world quickly and quietly. He passed peacefully. Our younger twin, Rafe, was not born until Tuesday 23, but died later that day in NeoNatal ICU.
Baby loss, and coping with grief, is very hard 1/ Quote over picture of a dar...
Nothing we could do. Just a horrible tragedy. We emerged from hospital a week ago shell shocked. We have taken some time out to recover. I am back at work part time, but bear with me. We will come through this, but will always miss our boys. Cards are fine, but pls no flowers 2/
The loss of our younger twin Rafe was particularly acute. He lived and died within a long day. But we treasure our time with him in Neonatal ICU. We were able to tell him of all our hopes and dreams for him, and our family; but he could not make it and died in Flora’s arms 3/
Read 6 tweets

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