Discover and read the best of Twitter Threads about #precautionary
Most recents (4)
Thread on why we have lodged an objection with Namibia's Environmental Commissioner regarding #ReconAfrica's planned 2D seismic surveys criss-crossing #elephant migration corridors across the Kavango regions of Namibia.
dailymaverick.co.za/article/2021-0…
dailymaverick.co.za/article/2021-0…
Our objection is coupled with a plea to employ the #precautionary principle to protect the largest cross-border #elephant herd from the harmful actions linked not only to seismic surveying but also from the ongoing exploratory #oil and #gas #drilling in #Namibia.
Seismic surveys help locate oil and gas reservoirs. It takes place by laying receptors called geophones along either a line (2D) or in a grid (3D) and detonating an explosive device, then recording the various soundwaves that are picked up by the geophones. Image: RBS 
#BillGates's #mosquito technological (naive) intervention, is a very bad idea, that I think emerges from the #Anthropocene framework. Thats why I has been pushing #Technocene instead, bc it tends to induce a more #precautionary approach:
frontiersin.org/articles/10.33…
RT @nntaleb
frontiersin.org/articles/10.33…
RT @nntaleb
*have
As a matter of fact, humans have coevolved with mosquitoes (biologically, cultural and technologically).. see our paper:researchers.one/article/2019-0…
SNEAK PREVIEW: Complete Path Enumeration (CPE) for CRM #dosefinding designs
Featuring a vignette for #Rstats package #precautionary update v0.2-3, currently under review by CRAN. 1/
precisionmethods.guru/DTAT/CPE/MCSE-…
Featuring a vignette for #Rstats package #precautionary update v0.2-3, currently under review by CRAN. 1/
precisionmethods.guru/DTAT/CPE/MCSE-…
This demonstrates the feasibility of a programme I’ve set forth, for the ‘exact’ simulation of ANY dose-escalation design.
Influenced by @MarkusTriska‘s exacting perspective on ’exactness’, however, I now use the more precise term ‘MCSE-free’. 2/
Influenced by @MarkusTriska‘s exacting perspective on ’exactness’, however, I now use the more precise term ‘MCSE-free’. 2/
@MarkusTriska ‘MCSE-free’ in turn alludes to the title of recent work by Thomas M. Braun, from which I adapt my application.
(Braun’s mean-field approach truly can be called ‘simulation-free’, whereas I DO simulate the trials—just without Monte Carlo error.) 3/
(Braun’s mean-field approach truly can be called ‘simulation-free’, whereas I DO simulate the trials—just without Monte Carlo error.) 3/
NEW #DTAT paper: What Were They Thinking? Pharmacologic priors implicit in a choice of 3+3 dose-escalation design arxiv.org/abs/2012.05301
“The unexamined trial is not worth conducting.”
— Socrates 1/
“The unexamined trial is not worth conducting.”
— Socrates 1/
This latest #DTAT paper @arxiv sets out to reverse-engineer the unstated (∴ unexamined!) pharmacologic intuitions that underlie the #trialsafety claim implicit in the decision to conduct a dose-escalation trial. 2/
Prior elicitation from doctors has never been easy, especially about #pharmacology or the future of the #Daleks: 3/
