Discover and read the best of Twitter Threads about #preeclampsia

Most recents (11)

We hope you enjoyed @ConwaySPHERE on @10Things_ToKnow last night on @RTEOne (catch us on here if you missed it )

But that's not all from us for this year's #ScienceWeekIreland ...

More details in thread (1/3) ⬇️
Wednesday Nov 10th @ConwaySPHERE will be featured on @RTEOne "Science to the Rescue" where we'll discuss our @scienceirel funded "AI For Societal Good" winning project #AI_PREMie & our goal to save lives of🤰+👶 from #preeclampsia

More details➡️…
Finally, Thurs Nov 11th for @scienceirel @DeptofFHed #CreatingOurFuture initiative we're hosting an awareness tea/coffee morning in @ucddublin to discuss thrombotic disorders & women’s health with @ThrombosisIrL& @UCDDiscovery
Read 4 tweets
Can you monitor maternal & fetal safety in clinical trials in pregnancy? Now you can, with #MFAET version 1.0 published this week @ISPDHQ
The 12 maternal & 19 fetal Adverse Event definitions are adopted by @MedDRAMSSO……
1/ Researchers @ucl @UCL_IfWH @UCLHresearch have developed a standard terminology for safety monitoring for pregnant women and their fetuses during development of drugs for pregnancy. #Pregnancy #AdverseEvents #MaternalSafety #fetus #MedDRA #MFAET…
2/ Adverse Event (AE) monitoring is central to assess therapeutic safety. The lack of an AE framework in pregnancy trials severely limits understanding risks in pregnant women. #MFAET was developed by international consensus of healthcare professionals & patient public groups.
Read 15 tweets
New research from @JohnsHopkins about maternal health!

Vaught AJ, Minhas A, Boyer T et al. Incidence of essential hypertension but not echocardiographic abnormalities at four years with a history of preeclampsia with severe features.

#ph260720 #Moms
In this new study, we followed up with women four years after they were diagnosed with preeclampsia during pregnancy. What type of research study is that?
#ph260720 #Epidemiology
Preeclampsia is a pregnancy-specific disorder that causes high blood pressure and evidence of damage to the kidneys and/or liver. Preeclampsia and other hypertensive disorders of pregnancy impact between 5-8% of births in the US.
#ph260720 #preeclampsia
Read 10 tweets
A metal ion orients SARS-CoV-2 mRNA to ensure accurate 2′-O methylation of its first nucleotide
The #SARSCoV2 #coronavirus is able to utilize the changes in metal ion concentrations to disguise itself in the human host body thus evading immune responses. Image
Efficacy of #clarithromycin on #COVID19 pneumonia without oxygen administration; protocol for multicenter, open-label, randomized-controlled, 3-armed parallel group comparison, exploratory trial #CAMECOVID
Japan Registry of Clinical Trials jRCTs071210011 Image
The influence of #HLA genotype on the severity of #COVID19 infection
A genetic link has been discovered explaining why some people catch #Covid but don't get sick. The gene is found three times as often in people who are #asymptomatic. Image
Read 199 tweets
🔝5 Concerns about #SARSCoV2 #Biology: A Call to Pause, Deliberate, and Revise Policy─This review is intended both as a basic resource and to initiate an open and critical dialog about SARS-CoV-2 biology for an independent and public call to action.…
Structural basis of ribosomal #frameshifting during translation of the #SARSCoV2 #RNA #genome
A unique feature of the SARS-CoV-2 genome controls protein synthesis and presents an "Achilles heel" of the virus. Image
Brainstem neuropathology in two cases of #COVID19: #SARSCoV2 trafficking between #brain and #lung
Neuropathologic evidence strongly suggests that the pathophysiology of COVID-19 related respiratory failure includes a neurogenic component. Image
Read 213 tweets
1/17 Taking forward the theme of #WorldKidneyDay let’s discuss what it means for “#WOMEN to live well with #kidney disease” 💃
🧵ahead is for anyone who cares about 💃!
@womeninnephro #womenempowerment #WomensDay #WomensHistoryMonth
Q-Do kidney diseases affect women differently?
Women have
⬆️Autoimmune diseases (SLE, RA, Systemic Scleroderma)
In #Women of Color that's 2- 3X commoner, early-onset with⬆️ complications

⬆️UTI due to short urethra
In #Pregnancy ⬆️risk of pyelonephritis and sepsis…
3/17 Pregnancy poses a high risk of #kidney injury due to various etiologies (see pic) which can progress to CKD in the future.
#Preeclampsia is a definite risk factor for #CKD and #ESKD in mother and also for #cardiovascular disease
Read 17 tweets
Excited to see our paper in @JCI_insight! Silver lining of lab shutdown this yr was time to wrap up this project which has been yrs in the making.

We studied a Stox1 KO mouse model to probe mechanisms underlying hypertensive disorders of #pregnancy. 1/…
STOX1 is a TF and predicted #preeclampsia risk gene IDed through family-based genetic linkage studies (van Dijk, @NatureGenet 2005). A variant in the DNA-binding domain was proposed to alter protein function ➡️ preE susceptibility. But LOF model had not been studied. 🐁 2/
*We found that loss of Stox1 ➡️ gHTN assd w placental hypoxia + abnormal ECM deposition.
*We observed activation of the uteroplacental renin-angiotensin system in Stox1 KO mice.
*Treatment w an ARB, losartan, rescued the gHTN phenotype, validating the mechanism. 3/
Read 4 tweets
Very important and high-yield #AIBD2020 session with @UmaMahadevanIBD on #IBD in #pregnancy! 🤰🔥💩👶

@IBDConference #GITwitter #GI #OBGYNtwitter #OBGYN
Management of a healthy pregnancy begins... before pregnancy!

#AIBD2020 @IBDConference @UmaMahadevanIBD #IBD
Start planning early!

Want 3 months of steroid-free remission before conception.

#AIBD2020 @IBDConference @UmaMahadevanIBD #IBD
Read 23 tweets
Wonderful talk at #AHA10 @MarilynCipolla on #preeclampsia and the Brain #neuroobstetrics #cardioobstetrics @uvmvermont @MaryCushmanMD
🧠Preeclampsia is vascular disorder
🧠Preeclampsia defined below @acog
🧠Once you have PE, greater 🫀 events, HTN, DM
🧠 But also BRAIN effects
#AHA20 #preeclampsia
🤰Preeclampsia is an exaggerated response of pregnancy induced inflammation, hyperlipidemia and hypercoagulation
⬆️ risk of:
🧠cognitive decline
🤰⬇️seizure threshold
🧠#preeclampsia ⬆️ this susceptibility

#AHA20 @AHAMeetings @nataliebello9
Read 6 tweets
1/ THREAD: #COVIDー19, Pregnancy, and #ACE2
A thought has been tugging at me for a few days. Currently, ACE inhibitors are pregnancy category C in the 1sr trimester and category D in the 2nd and 3rd trimesters.
#SARSCoV2 #COVID2019 #Covid_19…
2/ Teratogenicity, 1st trimester exposure to ACE inhibitors, and fetal anomalies/congenital malformations has been debated. Most malformations identified were various cardiac septal defects.…
3/ That being said, 2nd and 3rd trimester exposure to ACE inhibitors is associated with oligohydramnios, hypocalvaria, anuria, renal failure, neonatal hypotension, and patent ductus arteriosus.…
Read 13 tweets
Follow along as we live tweet the @FertStert journal club. What do you think about #uterinetransplant? #ASRM2019
Send your questions via Twitter to ask the panel! #ASRM2019
#uterine transplant is a treatment for absolute uterine factor infertility #ASRM2019
Read 24 tweets

Related hashtags

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3.00/month or $30.00/year) and get exclusive features!

Become Premium

Too expensive? Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal Become our Patreon

Thank you for your support!