Discover and read the best of Twitter Threads about #prevalence

Most recents (7)

This 30ish woman of mean height has a recurrent right spontaneous #PTX 18 months after the first. She has a history of thoracic pain receiving spinal steroid injections; o/w healthy. The best way to get the #diagnosis is (poll next) Image
The best way to get the diagnosis is:
Read 12 tweets
Do you #KnowyourHBVstatus? According to a study published in the Lancet Gastroenterology & Hepatology Journal, "Up to 90 percent of people living with hepatitis B virus (HBV) worldwide are unaware of their infection" doi.org/10.1016/S2468-…
#HBV #KnowyourHBVstatus #ph260720
Have you been tested for Hepatitis B? #HBV #KnowyourHBVstatus #ph260720
According to @WHO estimates, 257 million people worldwide are living with chronic HBV infection. In the US, the @CDC estimates that 862,000 people are living with chronic Hep B

#HBV #statistics #awareness #ph260720
Read 10 tweets
#WeekendLecture
#CerebralMicrobleeds #CMB

Radiological construct: small (2–10 mm diameter) round or ovoid #hypointense foci with associated #blooming with enhanced visibility on #MRI sequences sensitive to #susceptibility effects

thelancet.com/journals/laneu… ImageImage
#WeekendLecture
#CMB
🔬#Pathology: recent or old microhaemorrhages
🩸Microvessel injuries, ie: dilatation/fragmentation of the wall, amyloid-ß (in CAA) and fibrin extravasation
🩸Extravasation of red blood cells
🩸#hemosiderin-laden macrophages
karger.com/Article/FullTe… ImageImage
#WeekendLecture

In daily practice #CMB represents a radiological marker of #small vessel disease

In general:
🩸Strictly #lobar CMBs👉CAA
🩸Strictly #deep👉hypertension-related SVD ie #arteriolosclerosis
🩸Mixed 👉combination👆, but must think #hereditary #SVD, ie #CADASIL Image
Read 8 tweets
1/n: On the occasion of current discussions on testing strategies in #COVID19 let's make a short tweetorial on medical decision making (a branch of biomedical cybernetics, which is underestimated but has enormous impact). #cybernetics #biocybernetics #DecisionTheory
2/n: #Sensitivity, also known as "true positive rate" (TPR) is the fraction of the number of diseased subjects with positive test divided by all diseased patients. Since in both numerator and denominator are pure counts it is independent of the prevalence of the disease:
3/n: Likewise, the true-negative rate (TNR), the ratio of true negatives to the sum of false positives and true negatives, is independent of the prevalence:
Read 13 tweets
Daily Bookmarks to GAVNet 12/31/2020 greeneracresvaluenetwork.wordpress.com/2020/12/31/dai…
Sensemaking Reconsidered: Towards a broader understanding through phenomenology - Jörgen Sandberg, Haridimos Tsoukas, 2020

journals.sagepub.com/doi/full/10.11…

#understanding #sensemaking
Read 10 tweets
Thoughts on upcoming #COVID19 #serology tests:
This is actually quite a challenge! (#Diagnostics often involve a lot of complexities). There is a lot of pressure to roll these tests out, but they need to perform well, or we do more harm than good. #MicroRounds (A thread)
WHY we need these soon:
1. Contact tracing.
2. Can be used to test if a vaccine is working during a clinical trial (70 of them ongoing right now, I believe)
3. Inform public policy makers about rate of asymptomatic cases + previous infections/exposures =informed decision making
How is developing a #PCR different than developing a #serology test?
1. #PCR tests detect viral RNA/DNA (in this case RNA) and can be pretty straight-forward in terms of development
2. #Serology relies on knowing about the #SARSCoV2 structure and how the human body responds.
Read 13 tweets
Excited to share that our #GHB paper is now out in @AddictionJrnl.
With @RoseCrossin @foruharmoayeri @DebbieScott16 and team @TurningPointAU @MonashAddiction

bit.ly/GHBmeth
Trends in GHB‐related harms 2012‐2018 in Victoria
Spoiler alert, 147% rise
Highlights here->
What we did: looked at ambulance callouts for #GHB alone vs for co-use w other drugs (eg. #methamphetamine, #alcohol)
What we found: Overall #GHB presentations increased 147%, peaking in 2017 at 1339 callouts. This increase was largely driven by #GHB+#methamphetamine use together
#methamphetamine #ice co-use was >6x more likely to result in ambulance callouts than co-use with other drugs e.g. alcohol; and more #mentalhealth symptoms e.g. psychosis or anxiety.
Read 13 tweets

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