Discover and read the best of Twitter Threads about #primaryheadachedisorder

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2/ and presents with excruciating unilateral orbital, supraorbital, and/or temporal pain that lasts 15-180 minutes if left untreated. Patients also have ipsilateral autonomic symptoms during a cluster attack.
3/ Although the exact pathophysiology is unclear, the trigeminovascular pathway is important for the unilateral trigeminal distribution of pain, the trigeminal-autonomic reflex is important for producing ipsilateral cranial autonomic symptoms,
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