Discover and read the best of Twitter Threads about #prostaglandins
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1/6 PGE2 is one of the principal bioactive prostaglandins, critical signaling lipids implicated in body homeostais and pathegenic inflammatory response, yet its in vivo dynamics are largely unknown. #GRABsensors #Prostaglandins
2/6 Now we newly developed a fantastic GRAB-PGE2 sensor for monitoring PGE2 dynamics with high spatiotemporal resolution in vivo!
3/6 Using the newly developed GRAB-PGE2 sensor, we detected spatiotemporal PGE2 release during inflammation and seizures in the mouse dorsal cortex by mesoscopic imaging.
