Discover and read the best of Twitter Threads about #proteaseinhibitor
Most recents (3)
Ensitrelvir or S-217622, a potent inhibitor of SARCov2 main protease from Japan shows activity against COVID19 Variants of concern in animals studies and is poised to enter clinical trials.
#COVID19 #Ensiltrevir #Japan #ProteaseInhibitor #S217622
science.org/doi/10.1126/sc…
#COVID19 #Ensiltrevir #Japan #ProteaseInhibitor #S217622
science.org/doi/10.1126/sc…
Ensiltrevir blocks SARSCov2 Main protease after viral entry. #Ensiltrevir science.org/doi/10.1126/sc… 
Prophylactic treatment of S-217622 controls viral burden and disease in hamsters inoculated with SARS-CoV-2
science.org/doi/10.1126/sc…
science.org/doi/10.1126/sc…
@Pfizer @POTUS @TheDemocrats @VP @CNN @CBSNews @NBCNews @WKRN @WSMV @NC5
#Paxlovid #LongCovid #PACS #ProteaseInhibitor #Its2022FFS #WeDeserveBetter #DrugRepurposing
#Paxlovid #LongCovid #PACS #ProteaseInhibitor #Its2022FFS #WeDeserveBetter #DrugRepurposing
@pfizer @POTUS @TheDemocrats @VP @CNN @CBSNews @NBCNews @WKRN @WSMV @NC5 I have had the amazing opportunity to sit on Vanderbilt's HIV/AIDS Clinical Trials Community Advisory board since 2015 and want to shine a bright light on how therapeutics with SARS-Cov-2 should have been managed in the same way as HIV.
@pfizer @POTUS @TheDemocrats @VP @CNN @CBSNews @NBCNews @WKRN @WSMV @NC5 During the early years of the HIV/AIDS crisis, many were without any options. Then, AZT and other handfuls of medications were made available. Those who took it were literally guinea pigs. While supposition, I imagine escaping hospitalization and death were the metrics used.
In a world with #Omicron (a rare mutational event), the drug #molnupiravir (a mutagen) was just authorized by the @US_FDA despite:
1⃣ NO estimate of the number of mutations it causes per virus
2⃣ NO estimate of onward viral transmission while on the drug
fda.gov/news-events/pr…
1⃣ NO estimate of the number of mutations it causes per virus
2⃣ NO estimate of onward viral transmission while on the drug
fda.gov/news-events/pr…
@US_FDA Given #molnupiravir's usage to treat #COVID19 is inevitable, what can be done to prevent the potential acceleration of #SARSCoV2 variants?
1⃣patients should strictly ISOLATE WHILE TAKING, especially in the first days on the drug
2⃣ALL DOSES should be taken PRECISELY as directed
1⃣patients should strictly ISOLATE WHILE TAKING, especially in the first days on the drug
2⃣ALL DOSES should be taken PRECISELY as directed
@US_FDA Our own reasons for these recommendations are presented here 👇
