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💥Parathyroid Hormone-related Protein - PTHrP
⚡️Who was the first person to postulate the existence of PTHrP?
⚡️What is the mechanism of PTHrP mediated hypercalcemia of malignancy?
⚡️Does PTHrP have a physiological function?
#Onconephrology
#PTHrP
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⚡️Who was the first person to postulate the existence of PTHrP?
⚡️What is the mechanism of PTHrP mediated hypercalcemia of malignancy?
⚡️Does PTHrP have a physiological function?
#Onconephrology
#PTHrP
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Dr. Fuller Albright, in 1941, was the first to postulate the presence of a ‘substance’ that caused features of hyperparathyroidism in a cancer patient
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In this report, Dr. Albright essentially described the presence of PTH-like hormone in a cancer patient.
“I suspected that the tumor might be producing PTH. I therefore had it assayed but no PTH hormone was found”-Albright👇🏽
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nejm.org/doi/full/10.10…
“I suspected that the tumor might be producing PTH. I therefore had it assayed but no PTH hormone was found”-Albright👇🏽
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nejm.org/doi/full/10.10…
