Discover and read the best of Twitter Threads about #rNHC
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No doubt, #molnupiravir is touted as a ‘game changer’ as far as therapeutics against #SARS2 are concerned. But the news related to its probable #mutagenic potential comes as a dampener 1/
#rNHC, an active metabolite of #Molnupiravir, inhibits SARS2 replication in cell cultures through lethal mutagenesis, but is also mutagenic to mammalian host cells 2/
Read this paper👇
academic.oup.com/jid/article/22…
Read this paper👇
academic.oup.com/jid/article/22…
#rNHC has powerful in vitro and in vivo activity against a large number of highly pathogenic emerging RNA viruses and represents a potentially important drug for use in the current and future pandemics. 3/
