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New theoretical paper about the impact of Early Life #Adversity on the Amygdala “Amygdala Allostasis and Early Life Adversity: Considering Excitotoxicity and Inescapability in the Sequelae of Stress“ Quick 🧵 /1 psyarxiv.com/7gcuw
The amygdala is a heterogeneous group of clustered sub-nuclei; it plays a critical role in the evaluation of the emotional significance of incoming stimuli; and environmental experience has the potential to influence it due to amygdala's postnatal developmental trajectories /2
Preclinical & human research suggests adversity impacts amygdala structure; however, the magnitude and directionality have been inconsistent. This may be due to amygdala volume exhibiting an "inverted-U" pattern of alterations after ELA. /3)
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