Discover and read the best of Twitter Threads about #reagents
Most recents (2)
”I got tested for #COVID19 10 days ago and I don’t have a result! What’s taking so long????” This is a question I have heard many, many, times over the last 9 months. It is not everyone’s reality, but it does happen sometimes (Long thread alert) 1/14
Let’s talk about #COVID19 testing from the pathologist’s perspective (physicians like me who review and sign off on the validation studies in our labs so you can get tested amongst many other jobs; I need to do a what a pathologist does thread, but I digress) 2/14
In order for you to get PCR testing, it requires a swab and viral transport media (or VTM; it helps preserve the virus so the mRNA can be extracted later for testing, if it is present in the patient). Both of these items have been in short supply throughout the pandemic 3/14
Drawing Innovation: @illumina Super-Resolution Optics
Recently, $ILMN unveiled the NextSeq 2000, a mid-throughput sequencer w/ a ~2X reduction in operating costs ($/GB).
We think the upgrades inside the NextSeq 2000 may soon enable a $100 clinical-depth human #genome.
But how?
Recently, $ILMN unveiled the NextSeq 2000, a mid-throughput sequencer w/ a ~2X reduction in operating costs ($/GB).
We think the upgrades inside the NextSeq 2000 may soon enable a $100 clinical-depth human #genome.
But how?
The cost savings come from (1) a new upfront #chemistry and (2) super-resolution optics. We think @illumina will use real-world customer data on the NextSeq 2000 to optimize 1 and 2, then possibly upgrade the #NovaSeq line.
illumina.com/systems/sequen…
illumina.com/systems/sequen…
I'm going to briefly (!) illustrate how #sequencing (*by synthesis*) works, walk through a farming analogy, then dive into some technical details. (Sources at the end)
Below is a general overview of a whole genome sequencing workflow (sample in, data out).
Below is a general overview of a whole genome sequencing workflow (sample in, data out).
