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1/ Exactly the same theory was formalized by Russel Lande in 1976 and developed further by other evolutionary quantitative geneticists, and now the molecular biologists and medical scientists are re-discovering it in 2018 as "the omnigenic model" #ReinventingTheWheel
2/ The historical illitteracy and underappreciation of quantitative genetics as a tool from both molecular biologists and unfortunately also some molecularly oriented evolutionary biologists never stops to amaze me
3/ About ten years ago, when I discussed how to interpret and solve "the missing heritability problem" with a molecular ecology postdoc, I got the following (naive) suggestion: "Why not sequence more?"
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