Discover and read the best of Twitter Threads about #rheumedu

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#Methotrexate is the nr1⃣drug of choice for Rheumatoid #Arthritis.

MTX's history is eventful, and deserves a 🧵

🔹It started with childhood leukeamia
🔹Sleeping Beauty in the 1960-70's
🔹Awakened by Hoffmeister
🔹FDA👍1988 and 🔝 in the 1990's

1/🧵 #RheumTwitter #MedTwitter
The start:
🔹1948, Dr Farber treated 5 children with #leukemia with Aminopterin, an anti-folate & precursor of #MTX, with outstanding results

🔹1951, first positive results of Aminopterin in #RA & #Psoriasis pts

Despite this, Aminopterin was aborted in RA

2/🧵 #RheumTwitter
MTX enters:
Due to difficulties in manufacturing, Aminopterin was modified and MTX was created.

🔹1962, positive results with MTX in both RA and #PSA

🔹Next 10 years: MTX was extensively studied in #psoriasis but halted in #RA

🔹In RA, MTX becomes the Sleeping Beauty👸💤

3/🧵
Read 10 tweets
Un hilo 🧵 sobre podcasts de Reumatologia.
Una forma muy agradable de mantenerse al día desde cualquier lugar. A mi especialmente me gusta escucharlos temprano en la mañana tomando un café ☕️ #RotReuma
Comenzamos por Un Café por la Reumatologia , de los primeros en la especialidad y en español . Se encuentra en @GlobalRheum globalrheumpanlar.org/secciones/28/p…
Spotify open.spotify.com/episode/0FEbMW…
Apple podcasts.apple.com/co/podcast/glo…
El piloto se lanzó en junio 2019 globalrheumpanlar.org/podcast/un-caf… #podcast ImageImageImage
ACR on Air , podcast del @ACRheum conducido por @hausmannMD con episodios desde agosto del 2019 rheumatology.org/Learning-Cente…

Spotify open.spotify.com/show/5GU5M5Wmb…
Apple podcasts.apple.com/co/podcast/acr… Image
Read 18 tweets

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