Discover and read the best of Twitter Threads about #ringsideroblast
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There is an interesting history behind these cells, so familiar to hematologists & pathologists: ring (formerly 'ringed') sideroblasts. While most commonly associated with #MDS or inherited disorders like #XLSA, they can also result from ethanol or TB drugs - even hypothermia./1 
Sideroblasts and siderocytes - red cells and their precursors with iron granules in the cytoplasm visualized by a chemical reaction - were first described by Hans Grüneberg in 1942, a Jewish refugee from Germany working in London @ucl from 1933. /2
In 1955, Sven-Erik Björkman, working in Jan Gösta Waldenström's hematology unit @lunduniversity (thus far this tweetorial has 100% umlaut surnames!) noticed 4 of his anemic patients had weird sideroblasts: the iron granules encircled the nucleus. One of them developed leukemia./3
