Discover and read the best of Twitter Threads about #robust

Most recents (8)

2/4 "Adults have #clonally expanded exhausted #SARSCoV2-specific memory #Tcells."
3/4 "#Interferon-activated #naïve #Tcells differentiate into memory T cells in #adults but not #children."
Read 5 tweets
My contribution to the #electricity market debate, today at @voxeu
Thread 🧵…
1/Von der Leyen “Current electricity market design is not doing justice to consumers They should reap the benefits of lowcost renewables We will do a deep and comprehensive reform of electricity markets”…
Which should be the building blocks of the reform?
2/ On the objectives:
➡️*Productive efficiency*: demand must be met by the plants with the lowest marginal costs 📉📈
➡️*Investment efficiency*: investments must take place at the right scale, mix, and locations 🌞🍃
➡️*Equity*: prices should be cost-reflective 🪙
Read 17 tweets
Are there any changes in #brain #structure during the first year following #trauma #exposure? Is there a difference between individuals who develop #chronic #PTSD and those who #recover? A quick thread about our work published today in @molpsychiatry📜🧠🧵…
Reduced #hippocampus and #amygdala volumes have been repeatedly documented in #PTSD patients. But do they reflect a #pretrauma vulnerability trait or #postexposure stress-induced atrophy?
To answer this question, we examined the association between #longitudinal #volumetric #changes of the hippocampus and the amygdala, as well as their #key #subregions, and #PTSD #symptom #trajectories during the first #14months following #trauma exposure. Image
Read 10 tweets
These days, one of our 2019 working papers (@kielinstitute) by MEDAM researchers Claas Schneiderheinze & David Benček received substantial criticism from @m_clem, and is now being very much discussed.

A response.

The MEDAM research links rising #incomes with decreasing #emigration in poor countries thus challenging the causal interpretation of the “migration hump”.

2/6 Image
The critique is fundamental & sounds persuasive. @m_clem criticizes:
1) using annual data gives too much weight to bursts & busts
2) time fixed effects mask long-term econ. progress
3) the empirical setup with absolute emigration, GDP & population leads to spurious results

Read 6 tweets
Posting some reflections on the #ACTT & #RECOVERY trials related to #remdesivir & #dexamethasone for the treatment of #COVID19

Those results feel like definitive advances, but we need to realize their limitations and need for confirmation despite everyone's #pandemic fatigue

1/ Image
There are lot of skeptics in and outside of #Twitter on the results of both trials, strong emotions regarding big-pharma made medications, the way the #EUA was made, also about use of #steroids in the #ICU that has a quite rocky history among those who run those units.
And we need to acknowledge from the outset all sorts of basic, and not so basic, emotions that come in the doing clinical trials, exacerbated by academic cliques, national defense issues (and nationalisms) that can get exacerbated with the strains in health systems. Image
Read 21 tweets
1/ @STARRTAKI now published in @NEJM… – an updated thread follows below
#starrtaki #aki #FOAMcc @nephjc

@DrRonWald @CCCTG_ @anzicsctg @UKCCRGroup @ICCCTN @CIHR_IRSC @NIHRresearch @nhmrc @HRCNewZealand 🇨🇦🇦🇺🇦🇹🇧🇪🇧🇷🇨🇳🇩🇪🇫🇮🇫🇷🇮🇪🇮🇹🇳🇿🇨🇭🇺🇸🇬🇧
2/ Current CPGs do not make strong recommendations (Not Graded) on when to start RRT in ICU patients with AKI, in the absence of urgent indications, due largely to discrepant findings from prior RCTs ( ( @goKDIGO @NICEComms
3/ The @STARRTAKI trial is the largest multinational trial (168 sites, 15 countries) to address whether an accelerated (early) strategy compared with standard (delayed) strategy impacts mortality and kidney recovery in ICU patients with AKI #generalizability
Read 14 tweets
The #CoronaVirus or #Covid19 is a classic #BlackSwan event.

No one could see it coming. (Ok @BillGates did highlight risk of a pandemic - but realistically not many planned for this)

Such a chaotic event is catastrophic for those who are #Fragile,
A downturn for #Robust
Good for #Antifragile

(Channelling my inner NNT)
What is fragility?

As per @nntaleb checklist

- too much concentration of power (can’t talk back to authority with honest feedback)
- one trick pony (export one commodity)
- too much leverage (financial or over optimised supply chain)
- experience of previous crisis
Read 24 tweets
What do you do when you disagree with someone ? ... How do you handle a different perspective? ... I check we are talking about the same thing... consider the logic and evidence and finally stress test their conclusions...
I did that and I disagreed with @CarolineLucas my leader
First off @CarolineLucas is #spectacularly bright, #hardworking and a #visionary who pulled me into @TheGreenParty orbit. There are very few... perhaps no other UK politicians with a more determined record of standing up for our collective #environmental #rights #newgreenpolitics
Read 10 tweets

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