Discover and read the best of Twitter Threads about #rolacoaster

Most recents (2)

Part2️⃣
🍪
🍪🍪🍪🍪
🍪🍪Giant Cell🍪🍪
🍪🍪🍪Rich Tumors🍪🍪🍪
🍪🍪 of Bone 🍪🍪
🍪🍪🍪🍪
🍪

#BSTPath @ariella8 @VijayPatho @Path_Matt @AbhijitSurgPath
1/7
Remember this case❓

🔬 Yes! GCT of 🦴
(micro features in view of location + age + radiological/gross features)

Answer to Qs:
DDx based on epiphyseal location alone:
🦴GCT of bone
🦴Chondroblastoma
🦴Clear cell chondrosarcoma

#BSTPath @kriyer68
2/7

GCT of 🦴 continues....

☠️Secondary changes:
ABC, storiform fibrous histiocytoma-like, foam cells, focal osteoid

☠️H3F3A gene mutation (encoding histone 3.3): p.G34W

☠️IHC: G34W antibody staining the mononuclear cells

See:
Read 9 tweets
🍪🍪🍪🍪🍪🍪🍪🍪🍪🍪🍪
🍪🍪🍪🍪Giant Cells🍪🍪🍪🍪
🍪🍪🍪🍪🍪🍪🍪🍪🍪🍪🍪

Part1️⃣

1/6
What better way to kick-start the new year🎇than with a tweetorial/#RolaCoaster ?
Specifically made for the #pathtwitter family💝
Hope you enjoy the🎢!

#BSTPath @kells108 @natasharekhtman
2/6

Qs:
Can you tell these 2 giant-cell rich lesions apart❓🧐

Answer is coming in Part2️⃣ of this #Tweetorial

#BSTPath @kriyer68 @Histopatolomon @HENRYY_MD @ADamronMD @D4L14H @AlanPath @padmapathology1 @DrMarkOng @MBBS_Pathology
@Chucktowndoc @RunjanChetty @pembeoltulu
3/6

So…
▪️Why is this distinction difficult❓🤔
Because...
- Location is unknown
- Architecture not appreciated
- Age unknown

▪️Solution❓
- Radiology is 🔑
(closest thing to gross
specimen is the black/
white ‘negative’ image!)
Read 6 tweets

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