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Three scientific feats of ex vivo [organ] development

1) @WeizmannScience researchers are able to keep mouse embryos alive in a bottle for half of the normal in utero development

sciencemag.org/news/2021/03/m…
2) An array of papers that attempt producing human blastocysts from pluripotent cells, including from fibroblasts (the type of cell often used to make induced pluripotent stem cells).

May be important for learning about development
nature.com/articles/s4158…
sciencemag.org/news/2021/03/r…
3) Tear gland organoids that could produce tear fluid ("cry"), engineered in a dish. This could potentially in the future be useful for treating conditions such as Sjögren's syndrome, where tear production is severely lacking.

The gene Pax6 seems critical
nature.com/articles/d4158…
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