Discover and read the best of Twitter Threads about #sarcopenia

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At which age do we start to lose muscle mass?

A thread 馃У馃憞

#ageing #muscle #sarcopenia
Aging is associated with the loss of muscle mass. This phenomenon is also known as sarcopenia. Around what age does this start to occur?

2/
This study investigated the influence of age on muscle mass in a large sample of adults. Skeletal muscle mass was measured with a whole-body MRI for 468 adults of 18-88 years old. People that were bedridden, had physical disabilities, or had chronic illnesses were excluded.

3/
Read 7 tweets
驴El Omega 3 ayuda a ganar masa muscular?

Vamos con un hilo 馃憞馃У Image
El omega3 (EPA/DHA), se ha relacionado mucho con la hipertrofia muscular y la #fuerza. De hecho, si analizamos los estudios mecanicistas, vemos como el Omega 3 activa mTOR (s铆ntesis proteica muscular). Pero 驴existe un efecto real del omega 3 sobre la masa muscular y la fuerza?
Pues la respuesta corta es que no. La respuesta larga es que podr铆a ser, pero a煤n no tenemos suficientes datos sobre ello. Explico por qu茅:
Read 12 tweets
1/n A fascinating article came out this summer that argues for a plant-forward omni diet, and it contains a very inflammatory headline:

"Debunking the #vegan myth: The case for a plant-forward omnivorous whole-foods diet"

Note author Loren Cordain, a paleo proponent Image
2/n

The abstract:

"Veganism is without evolutionary precedent in Homo sapiens species. Strict adherence to a #vegan diet causes predictable deficiencies in nutrients including vitamins B12, B2, D, niacin, iron, iodine, zinc, high-quality proteins, omega-3, and calcium."
3/n

Let's review the images quickly because they show some of these dangers.

Fig. 1. Hazard ratios for all-cause mortality as calculated by Cox proportional hazards multi-variable regression analysis16. P = 0.082.

All cause mortality for #vegans and vegetarians is higher! Image
Read 17 tweets
Damos una vuelta en este #hilo a la
#Sarcopenia y #Envejecimiento?
TIPS:
1- La p茅rdida de masa muscular relacionada con la edad (llamada sarcopenia) tiene una prevalencia estimada del 10% en adultos mayores de 60 a帽os, que se eleva a >50% en adultos mayores de 80 a帽os
2- La p茅rdida de masa muscular es generalmente gradual, comenzando despu茅s de los 30 a帽os y acelerando despu茅s de los 60 a帽os . Estudios longitudinales previos han sugerido que la masa muscular disminuye en un 1,0-1,4% /anual
3- La contribuci贸n de las p茅rdidas de masa muscular..
a la disminuci贸n funcional est谩 mediada por la reducci贸n de la #FuerzaMuscular
鈿狅笍Ojo: La tasa de disminuci贸n de la fuerza muscular con la edad es de 2 a 5 veces mayor (隆!) que la disminuci贸n del tama帽o muscular
Por ello, se han establecido umbrales de debilidad muscular..
Read 7 tweets
Los 4 mecanismos fisiopatol贸gicos que explican la asociaci贸n entre la baja masa muscular y la funci贸n cognitiva #hilo 馃У馃У馃У馃憞

1鈨nflamaci贸n sist茅mica
2鈨esistencia a la Insulina
3鈨etabolismo de las prote铆nas
4鈨unci贸n mitocondrial
#Ejercicio #Sarcopenia
doi.org/10.1093/gerona鈥
1鈨nflamaci贸n sist茅mica馃巿
La contracci贸n del m煤sculo secreta citoquinas y p茅ptidos, llamados "mioquinas". Las mioquinas pueden ser tanto proinflamatorias como antiinflamatorias. #Next馃馃憞
doi.org/10.1038/nrrheu鈥
Por otro lado, las fibras musculares se clasifican en fibras d contracci贸n lenta tipo I y contracci贸n r谩pida tipo II. En las fibras de tipo II predomina una alta capacidad glucol铆tica, mientras q las fibras d tipo I comprenden un mayor contenido mitocondrial y capacidad oxidativa
Read 15 tweets
Vivir tres olas te hace ver que, como en el mar, comparten origen pero luego cada una crece y rompe con m谩s o menos fuerza.
Esta tercera ha llegado a la orilla con #fuerza y rabia, cuando a煤n no hab铆amos descansado de la segunda...
Con los meses tambi茅n nosotros hemos aprendido a saber como llegar谩n a la arena y a entenderlas un poco m谩s.
Si envolver谩n las piernas para luego escurrirse entre los pies o golpear谩n con fuerza haciendo caer unas piernas a las que vencer谩n sin esfuerzo por su #fragilidad.
Tras casi un a帽o, esa fragilidad, reforzada por un #confinamiento que nadie calculaba tan largo, multiplica los da帽os colaterales que el #virus de por s铆 lleva de serie.
#Paciente y familia esperan esa vuelta a casa,sin pensar en que tal vez las cosas no ser谩n como antes.
Read 12 tweets
Stop saying that higher protein intakes cause renal failure, you are wrong. From the WHO/FAO:
鈥溾he suggestion that the decline of glomerular filtration rate that occurs with advancing age in healthy subjects can be attenuated by reducing the protein content
in the diet has no foundation.鈥
From the IOM in setting the last DRI:
鈥溾rotein content of diet is not related to progressive decline in kidney function with age.鈥

A causal link? No evidence:
Changes in Kidney Function Do Not Differ between Healthy Adults Consuming
Higher- Compared with Lower- or Normal-Protein Diets: A Systematic Review and Meta-Analysis
academic.oup.com/jn/article/148鈥
A Systematic Review of Renal Health in Healthy Individuals Associated with Protein Intake above the US Recommended
Read 4 tweets
馃搯El 12 de Octubre se celebra #WorldArthritisDay 馃搯

馃棧锔廐ablamos de la #ArtritisReumatoide 馃棧锔

馃搶"The extra-articular impacts of #Rheumatoid Arthritis: moving towards holistic care"馃憣

馃敻Dolor
馃敻Fatiga
馃敻Ansiedad/Depresi贸n
馃敻Caquexia

馃敁馃敁猡碉笍猡碉笍#EULAR
ncbi.nlm.nih.gov/pubmed/30886982 Image
1鈨 Dolor

馃敻No todas las Causas son articulares
馃敻Es el #s铆ntoma que m谩s preocupa a los pacientes.
馃敻Es muy frecuente el Tto #Farmacol贸gico 馃拪, y no tanto #Ejercicio 馃弸锔忊嶁檪锔忦煆娾嶁檪锔#Fisioterapia 馃枑锔忦煣 #Psicol贸gico

馃憞馃憞馃憞 Image
2鈨 Ansiedad y Depresi贸n馃槹馃槯

馃敻Aparece con bastante frecuencia 馃搳
馃敻Diferentes causas de aparici贸n
馃敻Vuelve a aparecer tendencia a Tto Farmacol贸gico pero apenas #Psicol贸gico 馃馃棧锔忊灐锔廍scasez de medios
馃敻Gu铆a NICE para manejo 馃摉馃摎 Image
Read 6 tweets
馃毃馃毃Reci茅n Publicado 馃毃馃毃
馃挭馃挭P茅rdida de Masa muscular y su relaci贸n con #Osteoartritis #Artrosis 馃搶馃搶

馃摉鉁忥笍Abrimos #Hilo de #ArticuloFisio y Datos relevantes de #EjercicioTerap茅utico

馃摎Enlace aqu铆 猡碉笍猡碉笍 馃敁馃敁y #Openaccess
ncbi.nlm.nih.gov/pubmed/31203463 Image
La p茅rdida de Masa y Funci贸n Muscular 鉃★笍relaci贸n con la edad y la OA

馃搳12-19% 脕rea masa musc Corte transv 馃憠en OA rodilla y cadera
馃搳En cambio un 猬嗭笍猬嗭笍vasto medial cu谩driceps鉃★笍Mejoras s铆ntomas y estructural en OA rodilla.

馃Existen contradicciones en estudios por el t茅rmino...
... #sarcopenia el cual se DEBE diagnosticar con p茅rdida de
馃敻Masa
馃敻Fuerza
馃敻Funci贸n
馃敻Desarrollo de acts por parte del m煤sculo

Entonces 驴Antes el cambio muscular o la OA?
馃敼Hay estudios que ven la 鈴琺usc como factor Riesgo para OA
馃敼Otros que desuso por OA produce 鈴琺usc
Read 8 tweets
Physical Activity and Exercise 鈥撯撯撯 Their massive role in our health and wellness, at ALL ages/ stages of life.

A #curatedthread with tips and resources 鈥撯

Tags: #PhysicalActivity #Exercise #PhysicalMobility #SixthVitalSign #HealthyAging #health #wellness
More 鈥撯 #PhysicalActivity #Exercise #PhysicalMobility
Tips on Getting Started
m.gulfnews.com/news/europe/uk鈥
- Craft your 'why'/purpose
- Start slowly
- U may 'love' exercising OR Not
- Be kind to U
- Use 'why'& habit, Not willpower
- Plan,Prioritize
- Be flexible
-+Resistance, +Balance
More 鈥撯撯撯#PhysicalActivity #Exercise #PhysicalMobility #SixthVitalSign

"Common Sense Guide To Exercise and Moving More!" 鈥撯撯 by @CorKinetic

20 Great Tips! 馃憞
Read 52 tweets
What's the deal with Ammonia in hepatic encephalopathy?
A #cirrhosis QI #tweetorial

Aims
Try to answer this question while also showing
1) Ammonia levels dont matter
2) U should not restrict protein in patients with HE

Keywords: "ammonia hypothesis", sarcopenia
First, a poll:
Does Ammonia cause hepatic encephalopathy?
How did NH3 get involved with #HE in the first place?

Step 1: In 1877 Eck develops the first successful vascular anastamosis, a portocaval shunt. ncbi.nlm.nih.gov/pubmed/9186464
Step2: Pavlov improves it
Step3: Dogs get goofy after eating meat:"Meat stupor"
Step4: What's up with meat!?
Read 26 tweets
Thread: Decreasing muscle mass in aging: The harmful effects and how to counteract 鈥撯

Tags: #sarcopenia #aging #ageing #HealthyAging #MSKover50 #resistance training, #weights #physicalmobility #muscle, #protein
#osteoporosis #bone #fracture #falls

Image: iofbonehealth.org/what-sarcopenia
Thread: 馃斀muscle in #aging 鈥撯#Sarcopenia RX, prevention 鈥撯撯

#MSKover50 #resistance #physicalmobility #osteoporosis #bone #fracture #falls

Lifespan vs. Healthspan: Why We Need Muscle for #HealthyAging.
runnersworld.com/health-injurie鈥
+
Live Strong and Prosper...
link.springer.com/article/10.100鈥
Thread: Sarcopenia in #Aging: RX, prevention 鈥撯撯
馃斀
Biochemical Pathways of #Sarcopenia &Their Modulation by Physical #Exercise: A Narrative Review
frontiersin.org/articles/10.33鈥
H/T @MathewPiasecki Tags: #MSKover50
LT: Key RE: onset & progress
RT: Rec. of @ACSMNews & @American_Heart
Read 19 tweets

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