Discover and read the best of Twitter Threads about #scale

Most recents (24)

There's a lot of justified concern over whether #fermentation capacity can ever meet the promises of biotech at #scale. It's a real challenge, and one likely to present massive roadblocks to promising new companies, even with immediate action. 🧵
So much of #biotech is about proving that a microbe or genetic alteration can achieve X result in the lab, followed by the promise of what's possible "if you just scale this up…". Naturally, that last bit is where the true value proposition (and difficulty) lies.
Making lots of stuff, even with microscopic agents like yeast, requires gigantic steel tanks, and lots of them. For anything that offers global-scale solutions, we're talking many times more capacity than currently exists. But who's going to own and run all the tanks?
Read 15 tweets
Who else attended today's @OECD Development Co-operation Report 2021 launch event on shaping a just #DigitalTransformation?✋

Panelists expanded upon some of the report's key themes, including:

📅 Acting now!
⬆️ More #coordination
🖼️ Strong #frameworks
🧑‍🤝‍🧑 #InclusiveDevelopment
But we also heard a lot about #DigitalPublicGoods (#DPGs). Like... A LOT a lot.

So, what's the connection between #DPGs and a just, #inclusive #DigitalTransformation? Why have so many #donors, national #governments, and #tech experts alike expressed interest in #DPG solutions?
Well, they all agree that #DigitalTransformation is at a tipping point globally, with the divisions between wealthy and developing nations especially stark: 96% of the world's unconnected people live in developing countries.
Read 16 tweets
To make technology promises into reality, we must recognize Africa as a continent with 55 countries that are all different. Let's work with them to build what is required rather than serving them with one solution.
-Teki Akuetteh (@hub_adr)
Thank you to our great panel, everyone who contributed, and to all who attended.

Access the full "Development Co-operation Report 2021: Shaping a Just Digital Transformation"
👉 bit.ly/3v75TzW Image
@DIAL_Kate @Robert_Opp @SwarayRahman @SLMIC3 @MFAestonia @SocEcoCulDig_MW @BMZ_Bund @hub_adr @GSMA @UNDPDigital (1/3) Want to hear more about #DPGs and #DPIs from DIAL? Check out some of our resources!

Priya Vora and Jonathan Dolan's recent paper for @brookings asks, What is 'good' digital infrastructure? dial.global/research/what-…
Read 5 tweets
🔴 LIVE: Shaping A Just #DigitalTransformation, an @OECD high-level event where @DIAL_Kate will not only share her thoughts on the 2021 Development Co-operation Report's findings, but also share details about an exciting new effort we're proud to be leading with @DPGAlliance!
The new @OECD report highlights how to best achieve digital transformation by being responsive to digital realities, managing universal risks, and supporting gender action frameworks.
.@OECD's offer:
✅Going digital initiative
✅New research to accelerate #digitaltransformation
✅Inclusive forum to shape a digital future
✅DAC support participation of developing countries
Read 12 tweets
How the #DigitalDevelopment community thinks about sharing #information, #resources, and #data and partners to advance #DigitalTransformation will be key to creating #impact from our efforts and ensuring country #governments can replicate them to better serve their #citizens.
DIAL thinks about #partnerships in everything it does—in fact, were founded in 2015 by a partnership of #global #donors seeking to connect incredibly promising #DigitalDevelopment efforts that had failed to achieve #scale.
Read 20 tweets
The role of a #founder & #CEO needs to evolve over time and be aligned with #startup’s stage of maturity.

4 questions for 4 stages to help you focus:

How? —> #Idea stage
What? —> #Product market fit stage
Who? —> #Scale stage
Why? —> Big company stage

Thread 👇
#startups
1. #Idea stage. How?

“How will we make this idea a reality?”
This includes nailing down the pain in the market and articulating how you’re planning to cure that.
2. #Product-Market fit stage. What?

“What is the #market telling us?”
This includes looking at product-market fit indicators and iterating your #solution. If you’ve nailed the pain and know what are leading indicators of #PMF - this stage is actually easier than perceived.
Read 5 tweets
Back to work for a crucial year for UK Science, Research & Innovation & my core Missions:

🌏 ScienceSuperpower🧑🏽‍🔬
💥Innovation Nation👷🏼

Here are some of the Priorities in the NewYear in-tray:

1. Horizon: continue to push for UK association, alongside a bold GlobalBritain PlanB
2. Research Ecosystem: implementing the Nurse, Grant & Tickell Reviews of the UK Research landscape to
- improve career paths
- reduce bureaucracy
- accelerate decision-making
- boost UK global strengths in attracting top talent in
science🧬 & innovation💥
3. Oversee establishment of the new UK Advanced Research & Innovation Agency (ARIA) as the UK’s “Science Satellite” to ensure the UK stays on the frontline of exploring new ways of doing new science:
Read 16 tweets
Participated in an industry call this Am. It is obvious now that all municipalities will need to outsource waste collection to the big guys $GFL. Labor inflation hurting. Taxpayers will notice that municipalities operating own fleet are hemorrhaging cash. More wins coming $GFL.
In the US. ~20% of the industry is still Municipal. Should go to nearly 0% over time. Opportunity for solid waste winners with #scale
US + Canada is a $15 billion opportunity for scaled waste companies to replace municipal fleets. I expect $GFL to win more deals in the North East. $WCN to win the West. These deals are very high margin.
Read 4 tweets
You're struggling to scale your e-commerce #operations to a new level? Here are 5 easy ways on how to #scale horizontally👇🏻

THREAD 🧵 (1/6)
1️⃣ Foreign markets.

Chances are, that you're running your operations mainly in the United States of America. Think outside of the box. The world is big enough for you to scale in #untappedmarkets such as DACH, NORDIC, BENELUX, etc.

(2/6)
2️⃣ Foreign languages.

Not only should you consider #scaling in untapped markets as previously mentioned but you should also adapt to the local language. Tested this several times and it will significantly boost your #CVR and just overall performance-driven #KPIs.

(3/6)
Read 6 tweets
#WeekendLecture
#GeneticsAndStroke

#Genetics is involved in several #stroke related conditions, such as small vessel disease #SVD, aneurysms, dissections, cavernomas, and intracranial #hemorrhages

Check this 🧵!
Prepared by @J_Rosales_MD
Edited by @interneurona Image
#Weekendlecture

#Genetic & #SVD
🧬🧠

✅1,5% of cerebral #SVD are #monogenic disorders
✅AR, AD or X-linked
☝🏼Absence of family history doesn't rule out diagnosis because of
👉de novo mutation
👉reduced expression or
👉incomplete penetrance
ahajournals.org/doi/10.1161/ST…
#Weekendlecture

#Genetic & #SVD

When to #suspect?🕵️‍♀️

✅early onset stroke without vascular RFs
✅systemic features and neuroimaging of an specific monogenic disorder
✅consanguinity
✅negative work up for other causes of SVD

👉ahajournals.org/doi/10.1161/ST… Image
Read 15 tweets
We want to move @SafaricomPLC from being just a #telco with a #payment #platform #MoMo #mobilemoney #Mpesa to a #technology #company. Going into areas that are more #solutions oriented ... a #lifestyle brand for #individuals, and an empowering #brand for #SMEs@PeterNdegwa_
The #agile way of working is not new since it has been implemented by global #media and #online companies such as @netflix #netflix and @amazon #amazon
“What we are doing now is to #scale. Not everyone will go fully #agile, since departments like #Finance will still operate largely in its traditional way. But those that will be affected will be in the #frontend side of the company such as the #marketing and #technology teams.
Read 7 tweets
Today's question is on hiring and scaling a startup: Is it advisable for small companies or startups to hire a temporary consultant to build a team of developers and designers?

#agilemethodology #hiring #startup #scale #chieftechnologyofficer #cto #founder
If you’re hiring for more than 5 people, I’d personally hire a CTO, CPO or find a co-founder with prior experience in building teams first, and then work with a recruitment agency.
Because hiring or filling headcounts is not the end goal, you’ll need to make sure the new people are onboarded properly, and they have a roadmap to work on.
Read 4 tweets
Excited about new report w/Natalie Geismar: We believe a thriving #rural America is possible & central to America’s future. So we took a close look @ effectiveness of federal rural policy. Lots of takeaways on ways to #DoRightByRural. Thread👇1/
brookings.edu/research/reima…
Mindset shift needed by policymakers: #rural America more #diverse demographically & economically than most think. More than 1/5 Black & brown; significant entrepreneurialism; major service economy; less than 6% employed in ag. cc @urbaninstitute 2/
urban.org/urban-wire/deb…
A #rural agenda is integral to a #racialequity agenda – see @gbenga_ajilore @KatrinaEBadger.

And #rural will be central to successful #ClimateChange strategies w/large investments in clean energy infrastructure & shifts in food production. 3/
americanprogress.org/issues/economy…
Read 15 tweets
Here's the @NZGreens #energy policy thread @TheGreenParty. Find it here: greens.org.nz/energy_policy 1/n
1.10 (policy positions numbered👍) tax incentive of accelerated depreciation of investments that increase energy efficiency/renewable energy. Now we're talking @ProfBahaj @tom_rushby
1.11 establishing a #FeedInTariff to reward distributed micro-gen. Are you sure? They're being phased out elsewhere as their job is done (scaling market to reduce costs of tech). A fair grid import $ might be better?
Read 16 tweets
1/n #Thread on excerpts from an #essay "A #group is its own worst enemy" by Clay #Shirky ( #Social #software)

Original article can be found here - web.archive.org/web/2013120121…

or gwern.net/docs/technolog…
2/ hardly anybody really studies how to #design #software for human-to-human interaction.

so many of them just throw things together and allow themselves to be surprised by the social interactions that develop around their software.
#HCI
3/ As soon as the Internet happened, s/w stopped being solely about computer-to-human interaction and started being about human-to-human interaction. We had new applications like the Web, email, IM and forums, all of which were abt humans communicating with 1 another through s/w.
Read 17 tweets
Daily Bookmarks to GAVNet 6/09/2020-2

greeneracresvaluenetwork.wordpress.com/2020/06/09/dai…

Thousands of tons of ocean pollution can be saved by changing washing habits

phys.org/news/2020-06-t…

#pollution #washing #ocean
From Scalable Efficiency to Scalable Learning (#22)

medium.com/aperture-hub/f…

#efficiency #learning #scale
COVID 19 - Understanding the Unknown in Acute Respiratory Infections - CEBM

cebm.net/covid-19/covid…

#acute #unknown #respiratory #infections
Read 12 tweets
Daily Bookmarks to GAVNet 6/03/2020-2

greeneracresvaluenetwork.wordpress.com/2020/06/03/dai…

An interpretable mortality prediction model for COVID-19 patients | Nature Machine Intelligence

nature.com/articles/s4225…
#model #intelligence #machine #prediction #mortality
“Immune to Evidence”: How Dangerous Coronavirus Conspiracies Spread — ProPublica

propublica.org/article/immune…

#conspiracy #evidence #immune #spread
The public do not understand logarithmic graphs used to portray COVID-19 | LSE Covid-19

blogs.lse.ac.uk/covid19/2020/0…

#public #Graphics
Read 12 tweets
Daily Bookmarks to GAVNet 6/02/2020-2

greeneracresvaluenetwork.wordpress.com/2020/06/02/dai…

What COVID-19 Means For The Future Of Capitalism, Democracy And Sustainability

medium.com/volans/what-co…

#coronavirus #future #capitalism #democracy #Sustainability
U.S. COVID-19 Contact Tracing Programs Designed for Failure, Despite Bloomberg Money; Why Can't the U.S. Copy the Lessons of Hong Kong's Success? | naked capitalism

nakedcapitalism.com/2020/05/u-s-co…

#tracing #failure #contact #Bloomberg
Stretch and flow: Research sheds light on unusual properties of well-known materials

phys.org/news/2020-05-u…

#research #flow #materials #Stretch
Read 12 tweets
Daily Bookmarks to GAVNet 5/14/2020

Machine learning platform generates novel COVID-19 antibody sequences for experimental testing

phys.org/news/2020-05-m…
#MachineLearning #antibody
The Gaslighting Has Begun. Resist.

link.medium.com/yaNYXmQqd6
#power #scale #pandemic
Choices for the “New Normal” | Health Disparities | JAMA | JAMA Network

jamanetwork.com/journals/jama/…
#health #coronavirus
Read 8 tweets
#Storytelling.

Tonight I'm going to share highlights from the 2010 "Scenarios for the Future of Technology & Int'l Development" report produced by The Rockefeller Foundation & Global Business Network. Not just the "Lock Step" scenario, but all 4 scenarios. [54 page report]
Following Event 201 (Oct 18 2019), we must concede that the ruling class has been gifted with phenomenal and prophetic intuitions & insights. (They truly are the chosen ones.) Thus it is worthwhile, even mandatory, to study their scenario exercises & simulations.
"We believe that scenario planning has great potential for use in philanthropy to identify unique interventions... scenario planning allows us to achieve impact more effectively." [p 4]
Read 73 tweets
Let's go back to the basics today, and talk about some #morphology in the #dermatology exam.

Today's #tweetorial/#medthread will be about evaluating....

SCALE!

#MedEd #FOAMEd #dermtwitter #medtwitter #dermatologia pc:@dermnetnz
1/
Before we get too far into it, how do we think about #scale? Meaning, which one of the following is it?
2/
When we say "primary lesion," we mean the most basic element of a lesion/rash (papule, macule, patch, plaque etc).

SECONDARY CHANGE (which scale is) means the extra exam element that occurs on top of the primary lesion!

Tertiary/Quaternary isn't a thing. I'm just a jerk.
3/
Read 15 tweets
The only thing that will motivate people to #adapt newer #apps in already populated app #market is by declaring a Product Mature when it runs out of Visual Space that means ignoring dropdown menus & drawers completely. #UX #Trend #VisualCommunication #Design #DesignTrend #Product
Calling a Product Mature, gives it an identity. The age have passed, when learning a new software is considered a skill & achievement, integrated softwares are the necessary bridge to accomplish the task. Smaller #Visual Centric #Applications #Integrated in a #Pipeline are
Read 5 tweets
Just got to Davos. Ready to fill the leadership vacuum with big ideas. My focus will be on privilege and women. Only going to #womanels #methree. Also, my alligator-skin boots got snow on them, anyone have a blow drier or an FT I can use to dry them off?
Thread 1/n: Small ideas feel big when I'm in my Gulfstream, so here it goes: We have to innovate on innovation. The 7th industrial revolution disrupts AND displaces. Artificial intelligence and blockchain can only solve resurgent populism with #compassion.
2/n We elites are critical to making this debate glocalized. Thought leadership also involves thought stewardship. Communities form the core of our economies. Blue collar workers must be re-conceived as #newcollar workers. Code is key.
Read 31 tweets

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