Discover and read the best of Twitter Threads about #scarring

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I am very excited to introduce Interleukin-11 signaling as a global regulator of regeneration @ScienceAdvances! Huge thanks to @ReischauerSā€™s supervision and the co-authors for their support!
#regeneration #scarring #zebrafish
A thread. 1/n
Regeneration and scarring are the opposing endpoints after tissue damage. Mammals predominantly mount a fibrotic response, a root cause of many diseases. In contrast, cells in regenerative species undergo reprogramming, initiating a regenerative gene program. 2/n
We started by asking how quantitatively different these responses are. After cardiac injury, by lineage tracing fibroblasts and endothelial cells, we found ~10x less scar-forming myofibroblasts in the zebrafish heart when compared to what is known in adult mice. 3/n
Read 20 tweets
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All you need to know ahead of next week's #Budget in one... THREAD šŸ‘‡

1/19
#CovidEconomics
#BudgetSpeech2021
#EconTwitter
The #Budget2021 comes at a critical time when the UK is in the middle of battling the #pandemic and the economy is substantially weakened with uneven effects at industry, household & region level.

Read the economic context to #Budget2021 here šŸ‘‡

2/19
niesr.ac.uk/publications/uā€¦
We project the UK economy to contract again in 2021Q1 due to the second wave and the winter #lockdown as well as the effects of post-#Brexit adjustment, bringing #GDP to some 11% below pre-#pandemic levels

3/19
Read 19 tweets
What are the implications of excess global financial market volatility on economic growth? Are there threshold effects in the relationship between growth & excess global volatility for individual countries? How should we model the nonlinear effects in a multi-country setting? 1/n
We answer these questions in recent work with Alexander Chudik @DallasFed, M Hashem Pesaran @USCDornsife @TrinCollCam, @mraissi80 @IMFNews & @arebucci1 @JHUCarey @cepr_org @nberpubs: ideas.repec.org/p/cam/camdae/2ā€¦ #TGVAR 2/n
The #Covid19 #pandemic has been a shock like no other, initiating simultaneous demand and supply disruptions. In addition, it led to a sharp tightening in global #financial market conditions during the first quarter of 2020. 3/n Image
Read 23 tweets
In a recent paper, with Alexander Chudik @DallasFed, M Hashem Pesaran @USCDornsife, @mraissi80 @IMFNews & @arebucci1 @JHUCarey, we develop a threshold-augmented dynamic multi-country model (#TGVAR) to quantify the #macroeconomic effects of #Covid19: econ.cam.ac.uk/research/cwpe-ā€¦ 1/n Image
Key challenges with the empirical #economic analysis of #Covid19 include the following: how to identify the shock, how to account for its non-linear effects, & how to quantify its effects while accounting for spillovers, common global factors, network effects and uncertainty. 2/n
We contribute to the literature by addressing these issues in a coherent multi-country framework. We offer an identification strategy for the #Covid19 shock considering that a synthetic control method cannot be applied in the context of a global #pandemic. 3/n
Read 23 tweets

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