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📢 Very 🔥 out of press!

Our paper about #metabolic reprogramming in DC during development and activation.

OPEN ! (enjoy) nature.com/articles/s4146…
#natcomms

DC can 🔥 or🧯adaptive immune responses (IR). Also Metabolism can 🔥 or🧯 IR.

Little "zoom" on this story:👇

🧵 ImageImage
🤔 What are the metabolic profiles associated to inflammatory🔥 and tolerogenic 🧯👫 monocyte derived DCs?

Tools 🛠️ developed by us @SCENITHmetab (@CIML_Immunology), @felixjhartmann and others allowed us to address those questions.

(SCENITH) Image
👆
- A dramatic metabolic switch in monocytes one day after they start differentiation (top right).

Also:
How metabolic heterogeneity links to surface markers heterogeneity by #SCENITH (@SCENITHmetab & #scMEP in 🧯or 🔥 conditions

Check the nature.com/articles/s4146…

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