Discover and read the best of Twitter Threads about #sglt2inhibitors

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THREAD: SGLT2 inhibitors for #diabetes

1/5 Dr. Jamie Falk @jamisonfalk presented "A Deep Dive into #SGLT2i: What Comes to the Surface for Individuals with Diabetes"

👉🏽Watch the presentation here: bit.ly/3FRCEoM 🧑🏾‍💻

#T2DM #medsafety #FOAMed #MedEd
2/5 #AdverseEffects for #SGLT2i to be aware of: genital infections, hypovolemia, DKA, amputations

✅Check out the image ⬇️ for the risk estimates
✅Watch @JamisonFalk's presentation here: bit.ly/3FRCEoM🧑🏾‍💻

#T2DM #medsafety #FOAMed #MedEd #diabetes #ptsafety
3/5 Evidence to date for #SGLT2i:

The first of the two new classes of medications for type II diabetes to reduce ↘️ risk of CV #AdverseEvents and mortality

✅Watch @JamisonFalk's presentation here: bit.ly/3FRCEoM🧑🏾‍💻

#T2DM #medsafety #FOAMed #MedEd #diabetes
Read 6 tweets
SGLT2i Pearls:

1. SGLT2 inhibitors have significant long-term protection of GFR. However, because they cause afferent arteriolar vasoconstriction, expect to see an acute drop in GFR after initiating.
2. SGLT2 inhibitors work w/ ACEi/ARBs & can still provide improvement in renal outcomes for pts w/ diabetic kidney disease on max dose ACEi/ARB.

3. Patients already on thiazide can experience significant volume loss with SGLT2i initiation. Consider reducing or stopping thiazides
Read 18 tweets

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