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SGLT2i 💊 are emerging as a promising agent to prevent and ⤵️the progression of DKD
Ever wondered
What do they do to electrolytes❓
Why r these diuretics not associated with electrolyte depletion❓
Let's dive deeper🔓
#medtwitter #NephMadness #SGLT2iRegion
Ever wondered
What do they do to electrolytes❓
Why r these diuretics not associated with electrolyte depletion❓
Let's dive deeper🔓
#medtwitter #NephMadness #SGLT2iRegion
What is the impact of SGLT2i on Na and water hemostasis?
First, let’s revisit, how Na and glucose are handled in the nephron 📜
💥100% of the filtered glucose is reabsorbed along the nephron (90%, via SGLT2 in PCT)
💥1 Na+ ion for every glucose molecule gets absorbed from the lumen
💥In PCT 60 - 80% of sodium is reabsorbed
💥100% of the filtered glucose is reabsorbed along the nephron (90%, via SGLT2 in PCT)
💥1 Na+ ion for every glucose molecule gets absorbed from the lumen
💥In PCT 60 - 80% of sodium is reabsorbed
