Discover and read the best of Twitter Threads about #somite

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We are extremely happy to present our lab’s first #preprint! Together with @teamstembryo we identify #hypoxia as a major microenvironmental factor that governs ES cell lineage commitment.

biorxiv.org/content/10.110…

Short summary 👇🏼👇🏼 (1/11)
Have you ever wondered how environmental factors such as #hypoxia together with intrinsic cellular regulators shape stem cell identity and differentiation capacity? We have (a lot!). But wait a minute you say, isn’t oxygen essential for mammalian life? (2/11)
Of course it is! But… before placentation, the embryo develops in an increasingly hypoxic environment where oxygen tension is as low as 1.5%. But what’s the physiological relevance? @odedrechavi
(3/11)
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