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Use of the proper tests to analyze how immune t-cells (CD4+, CD8+) respond to SARS-CoV infection or vaccination, it's fairly clear SARS-CoV infection damages the CD8+ t-cells regardless of prior immunity.
Hybrid immunity is a false narrative.
Immunity debt is a false narrative
Hybrid immunity is a false narrative.
Immunity debt is a false narrative
Vaccination of patients induces robust CD4+ & CD8+ t-cell responses to the virus’ spike protein. In addition, these t-cells produced multiple types of cell-signaling molecules (cytokines), which recruit other immune cells—including antibody-producing B cells—to fight pathogens.
However, patients who had been infected with SARS prior to vaccination produced spike-specific CD8+ T cells at considerably lower levels—and with less functionality—than vaccinated people who had never been infected.
sciencedirect.com/science/articl…
sciencedirect.com/science/articl…
