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Here’s how #LymeDisease testing is rigged.
1. Allen #Steere discovered a genetic association between strong immune response & arthritis.
2. Only about 15% of people fit that profile
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1. Allen #Steere discovered a genetic association between strong immune response & arthritis.
2. Only about 15% of people fit that profile
Continued…
3. SmithKline needed to *not* diagnose #LymeDisease for their #LYMErix #vaccine trials
4. So they convinced the feds to rig the disease definition so a case of #Lyme = #LymeArthritis ONLY
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4. So they convinced the feds to rig the disease definition so a case of #Lyme = #LymeArthritis ONLY
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5. This is why #LymeDisease diagnostics are like antibody bingo—rigged to ID only the highly reactive arthritis-prone cases which represent a small minority
6. #LYMErix looked super effective in phase III because the tests would never DX more than 15% of cases!
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6. #LYMErix looked super effective in phase III because the tests would never DX more than 15% of cases!
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There is a lot of confusion about what #LymeDisease tests under the #CDC #twotier standard are actually designed to diagnose. I’d like to elucidate for all but am feeling kinda lazy, lol. Let’s see here. 1/x
Some think #lymeDisease diagnostics are geared toward #earlylyme only, while some say #latelyme or #LymeArthritis. It’s more specific than that & there is a reliance on timing & interpretation of results to exclude as many cases as possible. 2/x
First of all, one must understand that #LymeDisease & diagnostic test outcomes vary based on people’s genetic makeup, among other factors. People with certain HLAs (studied in-depth by #AllenSteere) tend to have a stronger immune response. 3/x
