Discover and read the best of Twitter Threads about #steppedwedge

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DEBATE: Should government #policy interventions evaluated in #stepped #wedge #trials be considered ‘research interventions’ and reviewed by the research ethics committee? An exchange in @ClinTrialsJ.
#researchethics #steppedwedge #REC
3/ “Our main point is that researchers should not have to obtain ethics committee approval for the intervention when they have had no part in its design and implementation but only want to evaluate it prospectively…”
Read 15 tweets
Proud to have led this #clusterRCT, presented @ESCCardio's #LBCT session & published today in @JAMA_current. Among 2495 adults (50% women) hospitalized for #HF, a transitional care model implemented in our publiclyfunded system did not ⬇️time to comp readmission/ED visit/death.
There was a significant improvement in the patient-reported outcomes of #discharge-preparedness, #qualityofcaretransition, and #QOL. However, there was no improvement in #QALY. The #PROs were not adjusted for multiplicity, but we will do post-hoc exploratory analysis.
Read 8 tweets

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