Discover and read the best of Twitter Threads about #stich
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📌#Revisión & #Metaanálisis. Revascularización en Cardiopatía Isquémica c/FEY <35%: para quienes y como.
4⃣ECR & 2.4K👥
🔹HEART (#HF #Revascularisation Trial)
🔸STICH (Surgical Treatment for #Ischemic HF)
🔹PARR-2 (PET and Recovery Following Revascularization)
🔸REVIVED-BCIS2
4⃣ECR & 2.4K👥
🔹HEART (#HF #Revascularisation Trial)
🔸STICH (Surgical Treatment for #Ischemic HF)
🔹PARR-2 (PET and Recovery Following Revascularization)
🔸REVIVED-BCIS2
🔹HEART (6%👥) FEY 24%. CABG vs OMT. Viabilidad todos.
🔸STICH/STICHES (49%👥) FEY 28%. CABG vs OMT. Viabilidad discrecional🩺.
🔹PARR-2 (17%👥) FEY 27%. tto guiado x imágenes
🔸REVIVED (28%👥) FEY 27%. PCI vs OMT. 14% TCI y 58% DA prox. Viabilidad todos.
👇Para guardar
🔸STICH/STICHES (49%👥) FEY 28%. CABG vs OMT. Viabilidad discrecional🩺.
🔹PARR-2 (17%👥) FEY 27%. tto guiado x imágenes
🔸REVIVED (28%👥) FEY 27%. PCI vs OMT. 14% TCI y 58% DA prox. Viabilidad todos.
👇Para guardar
📌Rol de la isquemia:
🔸Basado en estudios históricos: MASS II.
🔹STICH (nuclear) no mostró beneficio y sí un pequeño subanálisis del ISCHEMIA (gráfico)
🔸Aún👉recomendación clase I p/👥c/ enf. multivaso + isquemia inducible y FEY severa, aunque la evidencia actual no lo avala⛔️
🔸Basado en estudios históricos: MASS II.
🔹STICH (nuclear) no mostró beneficio y sí un pequeño subanálisis del ISCHEMIA (gráfico)
🔸Aún👉recomendación clase I p/👥c/ enf. multivaso + isquemia inducible y FEY severa, aunque la evidencia actual no lo avala⛔️
The #ISCHEMIA trial has been popular again in recent days on Twitter, but amongst all the controversies & criticisms, it got me thinking about the #STICH trial.
These two trials actually have quite a lot in common and it's worth exploring that in a little detail
A thread...1/
These two trials actually have quite a lot in common and it's worth exploring that in a little detail
A thread...1/
STICH was a government funded trial designed to answer definitively - for once and for all - the role of revascularization in ischaemic cardiomyopathy. Numerous observational and/or retrospective studies suggested benefit on 'hibernating myocardium' but the jury was still out 2/
It was a well-intentioned study with enormous amount of thought put into planning methodology, ensuring only experienced surgeons with proven good outcomes took part, OMT had to be maximized etc etc
Tragically, like other RCTs, STICH suffered from enormous enrollment bias...3/
Tragically, like other RCTs, STICH suffered from enormous enrollment bias...3/
