Discover and read the best of Twitter Threads about #substantivity

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SARS-COV-2 is a weak virus inactivated by many disinfectants/ mouthwashes. Challenge is not 'virus inactivation'. That's easy. Challenge is how long will salivary viral loads remain low after mouth rinsing. It needs a long acting mouthwash with persistent action #COVID19 (1/n)
.To minimize #COVID19 spread that happens by coughing, talking etc you need to keep the salivary viral loads low for sufficient time. Only those mouthwashes with strong intraoral attachment mechanisms & persistent action in saliva can do it. This property is "SUBSTANTIVITY" (2/n)
.Not all mouthwashes have substantivity. A mouthwash may easily kill #SARSCoV2 when tested outside the mouth. But most critical question is whether it will have any long acting effect "inside the mouth". Mouthwashes with no substantivity will not be able to do so. #COVID19 (3/n)
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