Discover and read the best of Twitter Threads about #tbrf

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[CASE REPORT] The CDC reports a case of Borrelia miyamotoi in California man: The Center for Disease Control (CDC) just published a case report In their journal, Emerging Infectious Disease, of Borrelia miyamotoi in California (continued in comments). #Lyme #Lymedisease #TBRF
1/7 The man was on a drug for multiple sclerosis, so he was considered immunocompromised. He experienced fevers that lasted a day, every 10-14 days, nausea, and “visual changes.”
2/7 Borrelia miyamotoi is a close cousin of Lyme disease and part of the tickborne relapsing fever group (TBRF).
Read 8 tweets
Joseph Burrascano, MD - Diagnostic Tools
#Lyme Clinical Presentation: nonspecific, viral-like symptoms that persist, & new ones appear. Then symptoms more focused on musculoskeletal, peripheral and central nervous systems, heart and skin. Muti-systemic & migratory. #ILADS2022 Image
2/Burrascano: Sorting out the co-infections #NotJustLyme #Bartonella #Babesia #Ehrlichia #Anaplasma #Mycoplasma #ILADS2022 ImageImageImageImage
3/Burrascano: Types of tests
SEROLOGIES are indirect, B-cell based tests:
B-cells create antibodies and serologies measure these antibodies #ILADS2022
Read 19 tweets
#idboardreview 25 M 1 wk post vacation in california mountain cabin: febrile x3d then felt better for 7d and now having fevers again, chills, myalgia, dyspnea progressed to ARDS. wbc3k, Hb11, plt20k, peripheral smear shown. Dx? vector? reservior? #idmeded #IDTwitter Image
#borrelia #hermsii vector: tick, reservoir: rodents
-In USA: spirochete in bloodstream: agents of tick borne relapsing fever #TBRF including B. hermsii
-Spirochetes: genera Spirochaeta, Treponema, Borrelia, Leptospira
-Other regions Borrelia recurrentis louse-borne relapsing F
Read 6 tweets
#idboardreview 30 M from western 🇺🇸 visited Middle East where symptoms of recurrent fevers >102F, headaches, myalgia, chills started
3 wks ago. Peripheral blood smear shown. Dx? #medEd #idmedEd #IDtwitter Image
Rick borne relapsing fever #TBRF #Borrelia persica inspired by jcm.asm.org/content/58/6/e… @ASMicrobiology pic ref P&P Mandell
median incubation period of 7d (range 2-18d): fever x 3d (range 2-7d), alternating w/ afebrile periods lasting about 7d range 4-14d)
If untreated #TBRF can have up to 30 relapses of febrile illness (most pts w/2 relapses)
whereas louse-borne illness is usually has only 1 relapse
Read 7 tweets

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