Discover and read the best of Twitter Threads about #tcell

Most recents (2)

1/ Continuing the #immunosuppression #tweetorial series...@MedTweetorials

Today's player: #mTORi, mammalian/mechanistic target of rapamcyin inhibitors

Rapamcyin was @US_FDA approved for #kidneytransplant in 2003.

It was isolated from a soil sample from which island in 1975?
2/ Meet mTOR, a phosphatidylinositol 3-kinase (PI3)-related kinase (adds a phos). mTOR adds a phosphoryl group to serine/threonine residues.

It is a key component of the complexes mTORC1 and mTORC 2 - which regulate processes including cell growth, proliferation, and survival.
3/ mTOR inhibition blocks "Signal 3" of #TCell activation - reducing cytokine dependent cell proliferation and activation.

Take a look at all 3 signals below ­čĹç­čĆŻ

nejm.org/doi/full/10.10ÔÇŽ
Read 11 tweets
(1/102) Yeni sistem deneysel #XN30 ├žal─▒┼čmam─▒z─▒n ilk serisini payla┼čal─▒m. Hen├╝z, eski sistemde yapt─▒─č─▒m ┼čekilde endeks grafi─čini haz─▒rlayamad─▒m olduk├ža uzun i┼člemci zaman─▒ gerektirdi─či i├žin. Zaman i├žerisinde olu┼čur ve haz─▒r oldu─čunda onu da payla┼čaca─č─▒m 3├ç sonunda.
(2/102) Daha kolay takip edilir/anla┼č─▒l─▒r olmas─▒ i├žin 274 elemanl─▒ s─▒ralama tablosunu 30'luk b├Âl├╝mlere ay─▒rd─▒m. ─░lk 30'luk tablo #XN30 endeksinin elemanlar─▒n─▒ olu┼čturmakta ve bir sonraki g├╝ncellemeya kadar takip edilen liste.
(3/102) Her tabloyu, i├žindeki hisselerin (30/tablo) grafikleri takip edecek ve sadece ilk 90 hissenin grafi─čini payla┼čaca─č─▒m. 274 grafik herkes i├žin biraz fazla, bana da yaz─▒k :)
Read 102 tweets

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